BC 2005 - breast cancer - analysis details: endpoints, steering files and strata

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Contents List

BC 2005 - breast cancer

BC 2005 run-time diktats
List of BC 2005 endpoints
List of BC 2005 non-breast second malignancies
BC 2005 endpoint definitions (awaiting re-write)
List of BC 2005 strata

Data structure and protocols for BC 2005

BC 2005 run-time diktats

Run-time estimation of unknown randomisation date

Set randomisation date to the earliest known date of:

Today
Contralateral breast cancer date
Second malignancy date(s)
Distant/unknown-site recurrence date
Locoregional recurrence date
Cut-off date (if any)
LFU/death date

Run-time estimation of unknown endpoint/censoring date, and adjustment of known censoring date

Set endpoint/censoring date to the latest known date of:

Randomisation date
Contralateral breast cancer date
Second malignancy date(s)
Distant/unknown-site recurrence date
Locoregional recurrence date

Run-time application of cut-off date, where relevant

If the randomisation date is later than the cut-off date, omit the case.
If the endpoint/censoring date is after the cut-off date, censor at the cut-off date instead.

Run-time estimation of unknown menopausal status

Entry age < 50: Premenopausal
Entry age 50+: Postmenopausal
Entry age unknown: Perimenopausal

Run-time estimation of unknown entry age (except for the detailed-age-stratified analyses)

Premenopausal: 40
Perimenopausal: 50
Other/unknown: 60

Run-time definition of 'probable breast cancer deaths'

Includes all deaths with recurrence or contralateral second primary, and those with 'unknown cause'

List of BC 2005 endpoints

	Endpoint	Mnemonic	Trial inclusion criteria
1	MORTALITY	DD
2	RECURRENCE-FREE SURVIVAL	RL	recurrence
3	BREAST CANCER MORTALITY (not used)	DDBC
4	DISTANT RECURRENCE	DIST	recurrence, site
5	MORTALITY FROM SECOND PRIMARY CANCER	DDPP	death cause
6	MORTALITY FROM UNKNOWN CAUSES WITHOUT RECORDED RECURRENCE	DDUKRL
7	MORTALITY FROM OTHER AND UNSPECIFIED NON-BREAST-CANCER CAUSES	NONBCUS	death cause
8	CARDIAC MORTALITY	HEART	death cause
9	MORTALITY FROM NON-BREAST-CANCER, NON-VASCULAR CAUSES	NONBCVASC	death cause
10	MORTALITY FROM LYMPHATIC AND HAEMATOPOIETIC CAUSES	DDLEUK	death cause
11	ENDOMETRIAL CANCER MORTALITY	DDENDO	death cause
12	MORTALITY FROM KNOWN NON-BREAST-CANCER CAUSES WITHOUT RECURRENCE	NONBC	death cause
13	VASCULAR MORTALITY	VASC	death cause
14	CONTRALATERAL BREAST CANCER AS FIRST EVENT	CONT	contralateral
15	ISOLATED LOCAL RECURRENCE AS FIRST EVENT	RLLI	recurrence, site
16	DISTANT RECURRENCE AS FIRST EVENT	RLD	recurrence, site
17	RECURRENCE	RLF	recurrence
18	MORTALITY OMITTING DEATHS FROM NON-BREAST-CANCER CAUSES WITHOUT RECURRENCE = (DD - NONBC)	DDPOSTREC
19	RECURRENCE AT UNKNOWN SITE AS FIRST EVENT	RLU	recurrence
20	RECURRENCE OMITTING ISOLATED LOCAL RECURRENCES AS FIRST EVENT = (RLF - RLLI)	RLNL	recurrence, site
21	MORTALITY AFTER ISOLATED LOCAL RECURRENCE AS FIRST EVENT	DDLI	recurrence, site
22	COLORECTAL CANCER MORTALITY	DDCOLO	death cause
23	ENDOMETRIAL CANCER INCIDENCE	ENDO	second malignancy
24	COLORECTAL CANCER INCIDENCE	COLO	second malignancy
25	SECOND PRIMARY CANCER INCIDENCE	PP	second malignancy
26	NON-CONTRALATERAL RECURRENCE AS FIRST EVENT	RLFNC	recurrence
27	RECURRENCE OMITTING NON-CONTRALATERAL AS FIRST EVENT = (RLF - RLFNC)	RLCONT	recurrence, contralateral
28	CEREBROVASCULAR MORTALITY	CEREB	death cause
29	OVARIAN CANCER MORTALITY	DDOVAR	death cause
30	THROMBOTIC AND EMBOLIC MORTALITY	DDTHEMB	death cause
31	PULMONARY EMBOLISM MORTALITY	DDPE	death cause
32	MORTALITY FROM EXTRANEOUS CAUSES	EXTRA	death cause
33	MORTALITY FROM KNOWN-SITE NON-ENDOMETRIAL SECOND PRIMARY CANCER	DDPPNE	death cause
34	MORTALITY FROM UNKNOWN-SITE CANCER	DDPPU	death cause
35	MORTALITY FROM IATROGENIC CAUSES	IATRO	death cause
36	PNEUMONIA MORTALITY	PNEUM	death cause
37	MORTALITY FROM UNSTATED CAUSES	DC0
38	MORTALITY FROM OTHER SPECIFIED CAUSES	DC9	death cause
39	MORTALITY FROM UNSPECIFIED NON-BREAST-CANCER CAUSES	DC10	death cause
40	MORTALITY FROM UNASCERTAINABLE CAUSES	DC12	death cause
41	MORTALITY FROM NON-PNEUMONIA RESPIRATORY CAUSES	DDRESP	death cause
42	MORTALITY FROM NON-CANCER HEPATIC CAUSES	DDHEP	death cause
43	MORTALITY FROM NON-PNEUMONIA INFECTIVE CAUSES	INFECTNP	death cause
44	MORTALITY FROM OTHER VASCULAR CAUSES	OVASC	death cause
45	OVARIAN CANCER INCIDENCE	OVAR	second malignancy
46	HEPATIC CANCER INCIDENCE	HEP	second malignancy
47	MORTALITY FROM HEPATIC CANCER	DDHEPC	death cause
48	MORTALITY FROM KNOWN NON-BREAST-CANCER CAUSES WITHOUT RECURRENCE, EXCLUDING ENDOMETRIAL CANCER	NONBCENDO	death cause
49	SECOND PRIMARY CANCER INCIDENCE AT KNOWN SITE	PPK	second malignancy
50	SECOND PRIMARY CANCER INCIDENCE AT UNKNOWN SITE	PPUK	second malignancy
51	LUNG CANCER INCIDENCE	LUNG	second malignancy
52	LEUKAEMIA AND LYMPHOMA INCIDENCE	LEUK	second malignancy
53	MORTALITY WITHOUT RECURRENCE	NONBCUK
54	MORTALITY WITH RECURRENCE (LOGRANK-SUBTRACTED) = (DD - NONBCUK)	DDPOSTRECB
55	MORTALITY OMITTING DEATHS FROM NON-BREAST-CANCER CAUSES (EXCLUDING ENDOMETRIAL CANCER) WITHOUT RECURRENCE = (DD - NONBCENDO)	DDPOSTRECC
56	SURVIVAL AFTER RECURRENCE	DDRL	recurrence
57	ISOLATED IPSILATERAL LOCAL RECURRENCE AS FIRST EVENT	RLILI	recurrence, site
58	MORTALITY FROM ACUTE MYELOID LEUKAEMIA	DDAML	death cause
59	ACUTE MYELOID LEUKAEMIA INCIDENCE	AML	second malignancy
60	UTERINE CANCER AS FIRST EVENT	UTER1	second malignancy
61	UTERINE CANCER MORTALITY	DDUTER	death cause
62	LEUKAEMIA OR LYMPHOMA AS FIRST EVENT	LEUK1	second malignancy
63	COLORECTAL CANCER AS FIRST EVENT	COLO1	second malignancy
64	LUNG CANCER AS FIRST EVENT	LUNG1	second malignancy
65	HEPATIC CANCER AS FIRST EVENT	HEPC1	second malignancy
66	OVARIAN CANCER AS FIRST EVENT	OVAR1	second malignancy
67	SECOND PRIMARY CANCER AS FIRST EVENT	PP1	second malignancy
68	CONTRALATERAL BREAST OR SECOND PRIMARY CANCER AS FIRST EVENT	PPCONT1	second malignancy, contralateral
69	LUNG CANCER MORTALITY	DDLUNG	death cause
70	NON-UTERINE SECOND CANCER AS FIRST EVENT	NONUPP1	second malignancy

List of BC 2005 non-breast second malignancies

Value	Description	ICD-7	ICD-8	ICD-9	ICD-10
-1	Further decision required	162 204 206-207 422 795 Excluding: 162.x 204.x	182 197 205-207 275 Excluding: 182.x 197.x 205.x-207.x 275.x	155 205-208 273 275 279 Excluding: 155.x 205.x-208.x 273.x	C22 C92-C95 O88 Excluding: C22.x C92.x-C95.x
1	Endometrial	172	182 Excluding: 182.9	182	C54
2	Colorectal	153-154	153-154	153-154	C18-C21
3	Ovarian	175	183	183	C56-C57
4	Primary liver	155	155	155.0-155.1	C22 Excluding: C22.9
5	Lung	162 Excluding: 162.2	162	162	C33-C34
6	AML (definite / probable / possible)	204.2-204.4	205-207 Excluding: 205.1 206.1 207.1	205-208 Excluding: 205.1 206.1 207.1 208.1	C92-C95 Excluding: C92.1 C93.1 C94.1 C95.1
7	Lymphatic and haematopoietic, non-AML	200-203 204.0-204.1 205	200-204 205.1 206.1 207.1 275.5	200-204 205.1 206.1 207.1 208.1 273.3	C81-C91 C92.1 C93.1 C94.1 C95.1 C96
8	Gastric	151	151	151	C16
9	Other second malignancy, site specified	140-197 Excluding: 151 153-156 162 (except 162.2) 170 172 175 191	140-194 Excluding: 151 153-155 162 173-174 182 (except 182.9) 183	140-194 Excluding: 151 153-155 162 173-174 182-183	C00-C75 C97 Excluding: C16 C18-C22 C33-C34 C44 C50 C54 C56-C57
10	Second malignancy	140-205 Excluding: 170 191	140-207 Excluding: 173-174	140-208 273.3 Excluding: 173-174	C00-C97 Excluding: C44 C50
11	Second malignancy, site specified	140-197 200-205 Excluding: 156 170 191	140-194 197.8 200-207 Excluding: 173-174	140-194 200-208 273.3 Excluding: 173-174	C00-C75 C81-C97 Excluding: C44 C50
12	Second malignancy, site unspecified	156 198-199	195-199 Excluding: 197.8	195-199	C76-C80
13	Uterine, part unspecified	174	182.9	179	C55
14	Liver, unspecified	-	197.8	155.2	C22.9

BC 2005 endpoint definitions (should be read in conjunction with Diktats)

PLEASE NOTE THAT THIS ENTIRE SECTION IS OUT OF DATE AND IS AWAITING A COMPLETE RE-WRITE!!!

Run-time strategy for data errors

Although efforts are made to create and maintain an 'error-free' database, numerous minor logical inconsistencies may persist during correspondence with trialists. In addition to the Diktats concerning missing dates etc, the following precepts are applied globally at run-time:

In addition to cases with 'distant/unknown-site recurrence' flags set, an unknown-site recurrence is taken to be present if a date of distant/unknown recurrence is present.
In addition to cases with 'locoregional recurrence' flags set, a locoregional recurrence is taken to be present if a date of distant/unknown recurrence is present.
In addition to cases with 'contralateral breast cancer' flags set, contralateral breast cancer is taken to be present if a date of contralateral breast cancer exists, except that if reported on (or before) the randomisation date (if non-null) it is disregarded throughout (with the exception of the 'CONT' endpoint, for which such cases are censored at the randomisation date).
In addition to cases with 'second malignancy (ICD)' reported, a second malignancy at unspecified site is taken to be present if a date of second malignancy is present.

CONT: CONTRALATERAL BREAST CANCER AS FIRST EVENT

An event is taken to have occurred if:

contralateral breast cancer is reported; and

the date of contralateral breast cancer does not exist and a recurrence is not reported; or
the date of contralateral breast cancer exists; and

a date of first recurrence does not exist or the date of first recurrence is on or later than the date of contralateral breast cancer; and
a date of first distant recurrence does not exist or the date of first distant recurrence is on or later than the date of contralateral breast cancer.

The event date is taken as the date of contralateral breast cancer.

If an event is not taken to have occurred, the case is censored at the randomisation date if the date of contralateral breast cancer is on or before the randomisation date, or else at THE EARLIEST OF the date died or last traced, the date of first recurrence (if non-null) and the date of first distant recurrence (if non-null).

DD: MORTALITY

An event is taken to have occurred if:

death has occurred.

The event date is taken as the date died.

If an event is not taken to have occurred, the case is censored at the date last traced.

DDPOSTREC: MORTALITY OMITTING DEATHS FROM NON-BREAST-CANCER CAUSES WITHOUT RECURRENCE

This endpoint is formed by subtraction of the annual events, (O - E) and variance of NONBC from DD, q.v.

DDUKRL: MORTALITY FROM UNKNOWN CAUSES WITHOUT RECORDED RECURRENCE

An event is taken to have occurred if:

death has occurred; and
the cause of death is 'unknown' or is not stated; and
a recurrence is not reported; and
contralateral breast cancer is not reported.

The event date is taken as the date died.

If an event is not taken to have occurred, the case is censored at the earliest of the date last traced, the date of first recurrence (if non-null), the date of first distant recurrence (if non-null) and the date of contralateral breast cancer (if non-null).

DIST: DISTANT RECURRENCE

An event is taken to have occurred if:

neither a recurrence nor contralateral breast cancer are reported and death has occurred from 'breast cancer'; or
a distant recurrence is reported and contralateral breast cancer is not reported; or
a date of first distant recurrence exists and the date of contralateral breast cancer exists and is after the date of first distant recurrence.

The event date is taken as the date of first distant recurrence (if any) or else the date died (if dead without recurrence) OR ELSE THE DATE DIED OR LAST TRACED (IF THE DATES OF BOTH FIRST RECURRENCE AND FIRST DISTANT RECURRENCE ARE UNKNOWN).

If an event is not taken to have occurred, the case is censored at the earliest of the date died or last traced, the date of contralateral breast cancer (if non-null) and, if death has occurred from 'unknown' or unstated cause, the date of first recurrence (if non-null).

DDENDO: ENDOMETRIAL CANCER MORTALITY

An event is taken to have occurred if:

death has occurred; and
the cause of death is 'other second neoplasm'; and
the death cause text begins '(d. endometrial' or ICD-7 codes 173, 174 or 233, ICD-8 codes 182 or 234 or ICD-9 code 182 are present; and
a recurrence is not reported; and
contralateral breast cancer is not reported.

The event date is taken as the date died.

HEART: CARDIAC MORTALITY

An event is taken to have occurred if:

death has occurred; and
the cause of death is 'heart'; and
a recurrence is not reported; and
contralateral breast cancer is not reported.

The event date is taken as the date died.

LEUK: MORTALITY FROM LYMPHATIC AND HAEMATOPOIETIC CAUSES

An event is taken to have occurred if: death has occurred; and the cause of death is 'lymphatic and haematopoietic'; and a recurrence is not reported; and contralateral breast cancer is not reported. The event date is taken as the date died. If an event is not taken to have occurred, the case is censored at the earliest of the date last traced, the date of first recurrence (if non-null), the date of first distant recurrence (if non-null) and the date of contralateral breast cancer (if non-null).

NONBC: MORTALITY FROM NON-BREAST-CANCER CAUSES WITHOUT RECURRENCE

An event is taken to have occurred if:

death has occurred; and
the cause of death is 'acute treatment toxicity', 'infective', 'lymphatic and haematopoietic', 'other second neoplasm', 'heart', 'thrombotic or embolic', 'other vascular', 'extraneous', 'not 1-8 and not breast cancer' or 'not breast cancer'; and
a recurrence is not reported; and
contralateral breast cancer is not reported.

The event date is taken as the date died.

NONBCUK: MORTALITY FROM UNKNOWN NON-BREAST-CANCER CAUSES

An event is taken to have occurred if: death has occurred; and the cause of death is 'not 1-8 and not breast cancer' or 'not breast cancer'; and a recurrence is not reported; and contralateral breast cancer is not reported. The event date is taken as the date died. If an event is not taken to have occurred, the case is censored at the earliest of the date last traced, the date of first recurrence (if non-null), the date of first distant recurrence (if non-null) and the date of contralateral breast cancer (if non-null).

NONBCVASC: MORTALITY FROM NON-BREAST-CANCER, NON-VASCULAR CAUSES

An event is taken to have occurred if:

death has occurred; and
the cause of death is 'acute treatment toxicity', 'infective', 'lymphatic and haematopoietic', 'other second neoplasm', 'extraneous' or 'not 1-8 and not breast cancer'; and
a recurrence is not reported; and
contralateral breast cancer is not reported.

The event date is taken as the date died.

DDPP: MORTALITY FROM SECOND PRIMARY CANCER

An event is taken to have occurred if:

death has occurred; and
the cause of death is 'other second neoplasm'; and
a recurrence is not reported; and
contralateral breast cancer is not reported.

The event date is taken as the date died.

RL: RECURRENCE-FREE SURVIVAL

An event is taken to have occurred if:

death has occurred; or
a recurrence is reported; or
contralateral breast cancer is reported.

The event date is taken as the earliest value of the date died (if dead), the date of first recurrence (if non-null) and the date of contralateral breast cancer (if non-null).

If an event is not taken to have occurred, the case is censored at the date last traced.

RLD: DISTANT RECURRENCE AS FIRST EVENT

An event is taken to have occurred if:

neither a recurrence nor contralateral breast cancer are reported and the trial/stratum does not lack recurrence site information and death has occurred from 'breast cancer'; or
A DISTANT RECURRENCE IS REPORTED AND CONTRALATERAL BREAST CANCER IS NOT REPORTED AND THE DATES OF FIRST RECURRENCE AND FIRST DISTANT RECURRENCE ARE BOTH UNKNOWN; OR
dates of first recurrence and first distant recurrence exist and the date of first distant recurrence is on or up to 7 days after the date of first recurrence; and

contralateral breast cancer is not reported; or
contralateral breast cancer is reported after the date of first distant recurrence.

The event date is taken as the date of first distant recurrence (if non-null) or else the date died (if dead from 'breast cancer' without recurrence) OR ELSE THE DATE DIED OR LAST TRACED (IF THE DATES OF FIRST RECURRENCE AND FIRST DISTANT RECURRENCE ARE BOTH UNKNOWN).

If an event is not taken to have occurred, the case is censored at the earliest of the date of first recurrence (if recurrence is present), the date died or last traced and the date of contralateral breast cancer (if non-null).

RLF: RECURRENCE AS FIRST EVENT

An event is taken to have occurred if:

neither a recurrence nor contralateral breast cancer are reported and death has occurred from 'breast cancer'; or
a recurrence is reported; and

contralateral breast cancer is not reported; or
contralateral breast cancer is reported and the date of contralateral breast cancer exists and the date of first recurrence exists and is before the date of contralateral breast cancer.

The event date is taken as the date of first recurrence (if non-null) or else the date died (if dead from 'breast cancer' without recurrence) OR ELSE THE DATE DIED OR LAST TRACED (IF THE DATES OF BOTH FIRST RECURRENCE AND FIRST DISTANT RECURRENCE ARE UNKNOWN).

If an event is not taken to have occurred, the case is censored at the earlier of the date died or last traced and the date of contralateral breast cancer (if non-null).

RLLI: ISOLATED LOCAL RECURRENCE AS FIRST EVENT

An event is taken to have occurred if:

a recurrence is reported and the trial/stratum does not lack recurrence site information; and

contralateral breast cancer is not reported; and

a first distant recurrence is not reported; or
dates of first recurrence and first distant recurrence exist and the date of first distant recurrence is more than 7 days after the date of first recurrence;

or contralateral breast cancer is reported and the dates of contralateral breast cancer and first recurrence exist and the date of first recurrence is before the date of contralateral breast cancer; and

a first distant recurrence is not reported; or
dates of first recurrence and first distant recurrence exist and the date of first distant recurrence is more than 7 days after the date of first recurrence.

The event date is taken as the date of first recurrence.

RLNL: RECURRENCE AS FIRST EVENT OMITTING ISOLATED LOCAL RECURRENCES AS FIRST EVENT

This endpoint is formed by subtraction of the annual events, (O - E) and variance of RLLI from RLF, q.v.

RLU: RECURRENCE AT UNKNOWN SITE AS FIRST EVENT

An event is taken to have occurred if:

neither a recurrence nor contralateral breast cancer are reported and the trial/stratum lacks recurrence site information and death has occurred from 'breast cancer'; or
contralateral breast cancer is not reported; or contralateral breast cancer is reported and the date of contralateral breast cancer exists and the date of first recurrence exists and is before the date of contralateral breast cancer; and a recurrence is reported and the trial/stratum lacks recurrence site information; or LOCAL RECURRENCE IS REPORTED ON A KNOWN DATE AND distant recurrence is reported on an unknown date.

The event date is taken as the date of first recurrence (if non-null) or else the date died (if dead from 'breast cancer' without recurrence).

If an event is not taken to have occurred, the case is censored at the earliest of the date died or last traced, the date of first recurrence (if non-null) and the date of contralateral breast cancer (if non-null).

VASC: VASCULAR MORTALITY

An event is taken to have occurred if:

death has occurred; and
the cause of death is 'heart', 'thrombotic or embolic' or 'other vascular'; and
a recurrence is not reported; and
contralateral breast cancer is not reported.

The event date is taken as the date died.

List of BC 2005 strata

Stratification

Mnemonic

Structure

Unstratified

Entry Age

	Stratum	Abbreviation
1	Entry age less than 50	Age < 50
2	Entry age 50 or more	Age 50+

Entry Age

	Stratum	Abbreviation
1	Entry age less than 40	Age < 40
2	Entry age 40 - 49	Age 40 - 49
3	Entry age 50 - 59	Age 50 - 59
4	Entry age 60 - 69	Age 60 - 69
5	Entry age 70 or more	Age 70+
6	Entry age unknown	Age unknown

Regrouping 8 of Entry Age

-3

	Stratum	Abbreviation
1	Entry age less than 40	Age < 40
2	Entry age 40 - 49	Age 40 - 49
3	Entry age 50 - 59	Age 50 - 59
4	Entry age 60 or more	Age 60+
5	Entry age unknown	Age unknown

Regrouping 29 of Entry Age

-4

	Stratum	Abbreviation
1	Entry age less than 50	Age < 50
2	Entry age 50 - 59	Age 50 - 59
3	Entry age 60 or more	Age 60+
4	Entry age unknown	Age unknown

Regrouping 42 of Entry Age

-5

	Stratum	Abbreviation
1	Entry age less than 50	Age < 50
2	Entry age 50 - 69	Age 50 - 69
3	Entry age 70 or more	Age 70+
4	Entry age unknown	Age unknown

Regrouping 48 of Entry Age

-6

	Stratum	Abbreviation
1	Entry age less than 50	Age < 50
2	Entry age 50 - 59	Age 50 - 59
3	Entry age 60 - 69	Age 60 - 69
4	Entry age 70 or more	Age 70+
5	Entry age unknown	Age unknown

Nodal Status

	Stratum	Abbreviation
1	N0, entry age less than 50	N0 < 50
2	N-, entry age less than 50	N- < 50
3	N1-3, entry age less than 50	N1-3 < 50
4	N4+, entry age less than 50	N4+ < 50
5	'Other' nodal status, entry age less than 50	N+/N? < 50
6	N0, entry age 50 or more	N0 50+
7	N-, entry age 50 or more	N- 50+
8	N1-3, entry age 50 or more	N1-3 50+
9	N4+, entry age 50 or more	N4+ 50+
10	'Other' nodal status, entry age 50 or more	N+/N? 50+

Regrouping 1 of Nodal Status

-1

	Stratum	Abbreviation
1	N0	N0
2	N-	N-
3	N1-3	N1-3
4	N4+	N4+
5	'Other' nodal status	N+/N?

Regrouping 2 of Nodal Status

-2

	Stratum	Abbreviation
1	N0/N-	N0/N-
2	N1-3	N1-3
3	N+/N?	N+/N?
4	N4+	N4+

Regrouping 3 of Nodal Status

-5

	Stratum	Abbreviation
1	N0/N-, entry age less than 50	N0/N- <50
2	N+, entry age less than 50	N+/N? <50
3	N0/N-, entry age 50 or more	N0/N- 50+
4	N+, entry age 50 or more	N+/N? 50+

E.R. Status

	Stratum	Abbreviation
1	ER-poor, entry age less than 50	ERpoor < 50
2	ER unknown, entry age less than 50	ER? < 50
3	ER+, entry age less than 50	ER+ < 50
4	ER++, entry age less than 50	ER++ < 50
5	ER-poor, entry age 50 or more	ERpoor 50+
6	ER unknown, entry age 50 or more	ER? 50+
7	ER+, entry age 50 or more	ER+ 50+
8	ER++, entry age 50 or more	ER++ 50+

Regrouping 4 of E.R. Status

-1

	Stratum	Abbreviation
1	ER-poor	ERpoor
2	ER unknown	ER?
3	ER+	ER+
4	ER++	ER++

Regrouping 5 of E.R. Status

-4

	Stratum	Abbreviation
1	ER-poor, entry age less than 50	ERpoor <50
2	ER unknown, entry age less than 50	ER? <50
3	ER+, entry age less than 50	ER+ <50
4	ER-poor, entry age 50 or more	ERpoor 50+
5	ER unknown, entry age 50 or more	ER? 50+
6	ER+, entry age 50 or more	ER+ 50+

Regrouping 12 of E.R. Status

-2

	Stratum	Abbreviation
1	ER-poor	ERpoor
2	ER unknown	ER?
3	ER+	ER+

Regrouping 14 of E.R. Status

-3

	Stratum	Abbreviation
1	ER-poor, entry age less than 50	ERpoor <50
2	ER+/unknown, entry age less than 50	ER+/? <50
3	ER-poor, entry age 50 or more	ERpoor 50+
4	ER+/unknown, entry age 50 or more	ER+/? 50+

Regrouping 15 of E.R. Status

-3

	Stratum	Abbreviation
1	ER-poor	ERpoor
2	ER+/unknown	ER+/?

P.R. Status

	Stratum	Abbreviation
1	PR-poor, entry age less than 50	PRpoor < 50
2	PR unknown, entry age less than 50	PR? < 50
3	PR+, entry age less than 50	PR+ < 50
4	PR++, entry age less than 50	PR++ < 50
5	PR-poor, entry age 50 or more	PRpoor 50+
6	PR unknown, entry age 50 or more	PR? 50+
7	PR+, entry age 50 or more	PR+ 50+
8	PR++, entry age 50 or more	PR++ 50+

Regrouping 6 of P.R. Status

-1

	Stratum	Abbreviation
1	PR-poor	PRpoor
2	PR unknown	PR?
3	PR+	PR+
4	PR++	PR++

Regrouping 7 of P.R. Status

-4

	Stratum	Abbreviation
1	PR-poor, entry age less than 50	PRpoor <50
2	PR unknown, entry age less than 50	PR? <50
3	PR+, entry age less than 50	PR+ <50
4	PR-poor, entry age 50 or more	PRpoor 50+
5	PR unknown, entry age 50 or more	PR? 50+
6	PR+, entry age 50 or more	PR+ 50+

Regrouping 13 of P.R. Status

-2

	Stratum	Abbreviation
1	PR-poor	PRpoor
2	PR unknown	PR?
3	PR+	PR+

Regrouping 16 of P.R. Status

-3

	Stratum	Abbreviation
1	PR-poor, entry age less than 50	PRpoor <50
2	PR+/unknown, entry age less than 50	PR+/? <50
3	PR-poor, entry age 50 or more	PRpoor 50+
4	PR+/unknown, entry age 50 or more	PR+/? 50+

Regrouping 17 of P.R. Status

-5

	Stratum	Abbreviation
1	PR-poor	PRpoor
2	PR+/unknown	PR+/?

Entry Age and Menop. Status

	Stratum	Abbreviation
1	Pre- and perimenopausal, entry age less than 50	Pre/Peri < 50
2	Postmenopausal, entry age less than 50	Post < 50
3	Pre- and perimenopausal, entry age 50 - 59	Pre/Peri 50-59
4	Postmenopausal, entry age 50 - 59	Post 50-59
5	All menopausal status, entry age 60 - 69	All 60-69
6	All menopausal status, entry age 70 or more	All 70+

Regrouping 31 of Entry Age and Menop. Status

-4

	Stratum	Abbreviation
1	Pre- and perimenopausal, entry age less than 50	Pre/Peri < 50
2	Postmenopausal, entry age less than 50	Post < 50
3	Pre- and perimenopausal, entry age 50 - 59	Pre/Peri 50-59
4	Postmenopausal, entry age 50 - 59	Post 50-59
5	All menopausal status, entry age 60 or more	All 60+

Nodal Status

	Stratum	Abbreviation
1	N0 clearance, entry age less than 50	N0 clear < 50
2	N+ clearance, entry age less than 50	N+ clear < 50
3	N- sampling/clinical, entry age less than 50	N- sam/clin <50
4	N+ sampling/clinical, entry age less than 50	N+ sam/clin <50
5	N unknown, entry age less than 50	N? < 50
6	N0 clearance, entry age 50 or more	N0 clear 50+
7	N+ clearance, entry age 50 or more	N+ clear 50+
8	N- sampling/clinical, entry age 50 or more	N- sam/clin 50+
9	N+ sampling/clinical, entry age 50 or more	N+ sam/clin 50+
10	N unknown, entry age 50 or more	N? 50+

Regrouping 10 of Nodal Status

-1

	Stratum	Abbreviation
1	N0 clearance	N0 clearance
2	N+ clearance	N+ clearance
3	N- sampling/clinical	N- sample/clin.
4	N+ sampling/clinical	N+ sample/clin.
5	N unknown	N unknown

Entry Age and Nodal Status

	Stratum	Abbreviation
1	Entry age less than 40, N0/N-	< 40, N0/N-
2	Entry age 40 - 49, N0/N-	40 - 49, N0/N-
3	Entry age 50 - 59, N0/N-	50 - 59, N0/N-
4	Entry age 60 - 69, N0/N-	60 - 69, N0/N-
5	Entry age 70+, N0/N-	70+, N0/N-
6	Entry age less than 40, N+/N?	< 40, N+/N?
7	Entry age 40 - 49, N+/N?	40 - 49, N+/N?
8	Entry age 50 - 59, N+/N?	50 - 59, N+/N?
9	Entry age 60 - 69, N+/N?	60 - 69, N+/N?
10	Entry age 70+, N+/N?	70+, N+/N?

Regrouping 37 of Entry Age and Nodal Status

-2

	Stratum	Abbreviation
1	Entry age less than 40, N0/N-	< 40, N0/N-
2	Entry age 40 - 49, N0/N-	40 - 49, N0/N-
3	Entry age 50 - 59, N0/N-	50 - 59, N0/N-
4	Entry age 60+, N0/N-	60+, N0/N-
5	Entry age less than 40, N+/N?	< 40, N+/N?
6	Entry age 40 - 49, N+/N?	40 - 49, N+/N?
7	Entry age 50 - 59, N+/N?	50 - 59, N+/N?
8	Entry age 60+, N+/N?	60+, N+/N?

Regrouping 36 of Entry Age and Nodal Status

-3

	Stratum	Abbreviation
1	Entry age less than 50, N0/N-	< 50, N0/N-
2	Entry age 50 - 59, N0/N-	50 - 59, N0/N-
3	Entry age 60 - 69, N0/N-	60 - 69, N0/N-
4	Entry age 70+, N0/N-	70+, N0/N-
5	Entry age less than 50, N+/N?	< 50, N+/N?
6	Entry age 50 - 59, N+/N?	50 - 59, N+/N?
7	Entry age 60 - 69, N+/N?	60 - 69, N+/N?
8	Entry age 70+, N+/N?	70+, N+/N?

Regrouping 30 of Entry Age and Nodal Status

-4

	Stratum	Abbreviation
1	Entry age less than 50, N0/N-	< 50, N0/N-
2	Entry age 50 - 59, N0/N-	50 - 59, N0/N-
3	Entry age 60+, N0/N-	60+, N0/N-
4	Entry age less than 50, N+/N?	< 50, N+/N?
5	Entry age 50 - 59, N+/N?	50 - 59, N+/N?
6	Entry age 60+, N+/N?	60+, N+/N?

Regrouping 11 of Entry Age and Nodal Status

-5

	Stratum	Abbreviation
1	N0/N-	N0/N-
2	N+/N?	N+/N?

Regrouping 39 of Entry Age and Nodal Status

-6

	Stratum	Abbreviation
1	Entry age less than 50, N0/N-	< 50, N0/N-
2	Entry age 50 - 69, N0/N-	50 - 69, N0/N-
3	Entry age 70+, N0/N-	70+, N0/N-
4	Entry age less than 50, N+/N?	< 50, N+/N?
5	Entry age 50 - 69, N+/N?	50 - 69, N+/N?
6	Entry age 70+, N+/N?	70+, N+/N?

Regrouping 53 of Entry Age and Nodal Status

-7

	Stratum	Abbreviation
1	Entry age less than 40	< 40
2	Entry age 40 - 49	40 - 49
3	Entry age 50 - 59	50 - 59
4	Entry age 60 - 69	60 - 69
5	Entry age 70 or more	70+

Regrouping 54 of Entry Age and Nodal Status

-8

	Stratum	Abbreviation
1	Entry age less than 50	< 50
2	Entry age 50 - 69	50 - 69
3	Entry age 70 or more	70+

Regrouping 55 of Entry Age and Nodal Status

-9

	Stratum	Abbreviation
1	Entry age less than 50	< 50
2	Entry age 50 - 59	50 - 59
3	Entry age 60 - 69	60 - 69
4	Entry age 70 or more	70+

Nodal Status (pathological overrides clinical where both available)

	Stratum	Abbreviation
1	N0 clearance, entry age less than 50	N0 clear < 50
2	N+ clearance, entry age less than 50	N+ clear < 50
3	N- sampling/clinical, entry age less than 50	N- sample/clin <50
4	N+ sampling/clinical, entry age less than 50	N+ sample/clin <50
5	N unknown, entry age less than 50	N? < 50
6	N0 clearance, entry age 50 or more	N0 clear 50+
7	N+ clearance, entry age 50 or more	N+ clear 50+
8	N- sampling/clinical, entry age 50 or more	N- sample/clin 50+
9	N+ sampling/clinical, entry age 50 or more	N+ sample/clin 50+
10	N unknown, entry age 50 or more	N? 50+

Regrouping 10 of Nodal Status

-1

	Stratum	Abbreviation
1	N0 clearance	N0 clearance
2	N+ clearance	N+ clearance
3	N- sampling/clinical	N- sample/clin.
4	N+ sampling/clinical	N+ sample/clin.
5	N unknown	N unknown

Nodal Status

	Stratum	Abbreviation
1	N0 clearance	N0 clearance
2	N+ clearance	N+ clearance
3	N- sampling	N- sampling
4	N+ sampling	N+ sampling
5	N- clinical	N- clinical
6	N+ clinical	N+ clinical
7	N- unk. method	N- unk. method
8	N+ unk. method	N+ unk. method
9	N unknown	N unknown

Entry Age and Menop. Status

	Stratum	Abbreviation
1	All menopausal status, entry age less than 40	All < 40
2	Pre- and perimenopausal, entry age 40 - 49	Pre/Peri 40-49
3	Postmenopausal, entry age 40 - 49	Post 40-49
4	Pre- and perimenopausal, entry age 50 - 59	Pre/Peri 50-59
5	Postmenopausal, entry age 50 - 59	Post 50-59
6	All menopausal status, entry age 60 - 69	All 60-69
7	All menopausal status, entry age 70 or more	All 70+

Nodal and E.R. Status

	Stratum	Abbreviation
1	N0/N-, ER-poor, entry age less than 50	N0/N- ERpoor < 50
2	N0/N-, ER unknown, entry age less than 50	N0/N- ER? < 50
3	N0/N-, ER+, entry age less than 50	N0/N- ER+ < 50
4	N+/N?, ER-poor, entry age less than 50	N+/N? ERpoor < 50
5	N+/N?, ER unknown, entry age less than 50	N+/N? ER? < 50
6	N+/N?, ER+, entry age less than 50	N+/N? ER+ < 50
7	N0/N-, ER-poor, entry age 50 or more	N0/N- ERpoor 50+
8	N0/N-, ER unknown, entry age 50 or more	N0/N- ER? 50+
9	N0/N-, ER+, entry age 50 or more	N0/N- ER+ 50+
10	N+/N?, ER-poor, entry age 50 or more	N+/N? ERpoor 50+
11	N+/N?, ER unknown, entry age 50 or more	N+/N? ER? 50+
12	N+/N?, ER+, entry age 50 or more	N+/N? ER+ 50+

Regrouping 24 of Nodal and E.R. Status

-1

	Stratum	Abbreviation
1	N0/N-, ER-poor	N0/N- ERpoor
2	N0/N-, ER unknown	N0/N- ER?
3	N0/N-, ER+	N0/N- ER+
4	N+/N?, ER-poor	N+/N? ERpoor
5	N+/N?, ER unknown	N+/N? ER?
6	N+/N?, ER+	N+/N? ER+

Regrouping 20 of Nodal and E.R. Status

-3

	Stratum	Abbreviation
1	N0/N-, ER-poor, entry age less than 50	N0/N- ERpoor < 50
2	N0/N-, ER+/unknown, entry age less than 50	N0/N- ER+/? < 50
3	N+/N?, ER-poor, entry age less than 50	N+/N? ERpoor < 50
4	N+/N?, ER+/unknown, entry age less than 50	N+/N? ER+/? < 50
5	N0/N-, ER-poor, entry age 50 or more	N0/N- ERpoor 50+
6	N0/N-, ER+/unknown, entry age 50 or more	N0/N- ER+/? 50+
7	N+/N?, ER-poor, entry age 50 or more	N+/N? ERpoor 50+
8	N+/N?, ER+/unknown, entry age 50 or more	N+/N? ER+/? 50+

Regrouping 22 of Nodal and E.R. Status

-5

	Stratum	Abbreviation
1	N0/N-, ER-poor	N0/N- ERpoor
2	N0/N-, ER+/unknown	N0/N- ER+/?
3	N+/N?, ER-poor	N+/N? ERpoor
4	N+/N?, ER+/unknown	N+/N? ER+/?

Regrouping 56 of Nodal and E.R. Status

-6

	Stratum	Abbreviation
1	ER-poor, entry age less than 50	ERpoor, < 50
2	ER+/unknown, entry age less than 50	ER+/?, < 50
3	ER-poor, entry age 50 or more	ERpoor, 50+
4	ER+/unknown, entry age 50 or more	ER+/?, 50+

Regrouping 63 of Nodal and E.R. Status

-7

	Stratum	Abbreviation
1	ER-poor, entry age less than 50	ERpoor, < 50
2	ER unknown, entry age less than 50	ER?, < 50
3	ER+, entry age less than 50	ER+, < 50
4	ER-poor, entry age 50 or more	ERpoor, 50+
5	ER unknown, entry age 50 or more	ER?, 50+
6	ER+, entry age 50 or more	ER+, 50+

Nodal and P.R. Status

	Stratum	Abbreviation
1	N0/N-, PR-poor, entry age less than 50	N0/N- PRpoor < 50
2	N0/N-, PR unknown, entry age less than 50	N0/N- PR? < 50
3	N0/N-, PR+, entry age less than 50	N0/N? PR+ < 50
4	N+/N?, PR-poor, entry age less than 50	N+/N? PRpoor < 50
5	N+/N?, PR unknown, entry age less than 50	N+/N? PR? < 50
6	N+/N?, PR+, entry age less than 50	N+/N? PR+ < 50
7	N0/N-, PR-poor, entry age 50 or more	N0/N- PRpoor 50+
8	N0/N-, PR unknown, entry age 50 or more	N0/N- PR? 50+
9	N0/N-, PR+, entry age 50 or more	N0/N- PR+ 50+
10	N+/N?, PR-poor, entry age 50 or more	N+/N? PRpoor 50+
11	N+/N?, PR unknown, entry age 50 or more	N+/N? PR? 50+
12	N+/N?, PR+, entry age 50 or more	N+/N? PR+ 50+

Regrouping 25 of Nodal and P.R. Status

-1

	Stratum	Abbreviation
1	N0/N-, PR-poor	N0/N- PRpoor
2	N0/N-, PR unknown	N0/N- PR?
3	N0/N-, PR+	N0/N? PR+
4	N+/N?, PR-poor	N+/N? PRpoor
5	N+/N?, PR unknown	N+/N? PR?
6	N+/N?, PR+	N+/N? PR+

Regrouping 21 of Nodal and P.R. Status

-3

	Stratum	Abbreviation
1	N0/N-, PR-poor, entry age less than 50	N0/N- PRpoor < 50
2	N0/N-, PR+/unknown, entry age less than 50	N0/N- PR+/? < 50
3	N+/N?, PR-poor, entry age less than 50	N+/N? PRpoor < 50
4	N+/N?, PR+/unknown, entry age less than 50	N+/N? PR+/? < 50
5	N0/N-, PR-poor, entry age 50 or more	N0/N- PRpoor 50+
6	N0/N-, PR+/unknown, entry age 50 or more	N0/N- PR+/? 50+
7	N+/N?, PR-poor, entry age 50 or more	N+/N? PRpoor 50+
8	N+/N?, PR+/unknown, entry age 50 or more	N+/N? PR+/? 50+

Regrouping 23 of Nodal and P.R. Status

-5

	Stratum	Abbreviation
1	N0/N-, PR-poor	N0/N- PRpoor
2	N0/N-, PR+/unknown	N0/N- PR+/?
3	N+/N?, PR-poor	N+/N? PRpoor
4	N+/N?, PR+/unknown	N+/N? PR+/?

Entry Age and E.R. Status

	Stratum	Abbreviation
1	Entry age less than 40, ER-poor	< 40, ERpoor
2	Entry age 40 - 44, ER-poor	40 - 44, ERpoor
3	Entry age 45 - 49, ER-poor	45 - 49, ERpoor
4	Entry age 50 - 54, ER-poor	50 - 54, ERpoor
5	Entry age 55 - 59, ER-poor	55 - 59, ERpoor
6	Entry age 60 - 69, ER-poor	60 - 69, ERpoor
7	Entry age 70 or more, ER-poor	70+, ERpoor
8	Entry age less than 40, ER unknown	< 40, ER?
9	Entry age 40 - 44, ER unknown	40 - 44, ER?
10	Entry age 45 - 49, ER unknown	45 - 49, ER?
11	Entry age 50 - 54, ER unknown	50 - 54, ER?
12	Entry age 55 - 59, ER unknown	55 - 59, ER?
13	Entry age 60 - 69, ER unknown	60 - 69, ER?
14	Entry age 70 or more, ER unknown	70+, ER?
15	Entry age less than 40, ER+	< 40, ER+
16	Entry age 40 - 44, ER+	40 - 44, ER+
17	Entry age 45 - 49, ER+	45 - 49, ER+
18	Entry age 50 - 54, ER+	50 - 54, ER+
19	Entry age 55 - 59, ER+	55 - 59, ER+
20	Entry age 60 - 69, ER+	60 - 69, ER+
21	Entry age 70 or more, ER+	70+, ER+

Regrouping 18 of Entry Age and E.R. Status

-2

	Stratum	Abbreviation
1	Entry age less than 50, ER-poor	< 50, ERpoor
2	Entry age 50 - 59, ER-poor	50 - 59, ERpoor
3	Entry age 60 or more, ER-poor	60+, ERpoor
4	Entry age less than 50, ER unknown	< 50, ER?
5	Entry age 50 - 59, ER unknown	50 - 59, ER?
6	Entry age 60 or more, ER unknown	60+, ER?
7	Entry age less than 50, ER+	< 50, ER+
8	Entry age 50 - 59, ER+	50 - 59, ER+
9	Entry age 60 or more, ER+	60+, ER+

Regrouping 19 of Entry Age and E.R. Status

-3

	Stratum	Abbreviation
1	Entry age less than 40, ER-poor	< 40, ERpoor
2	Entry age 40 - 44, ER-poor	40 - 44, ERpoor
3	Entry age 45 - 49, ER-poor	45 - 49, ERpoor
4	Entry age 50 - 54, ER-poor	50 - 54, ERpoor
5	Entry age 55 - 59, ER-poor	55 - 59, ERpoor
6	Entry age 60 - 69, ER-poor	60 - 69, ERpoor
7	Entry age 70 or more, ER-poor	70+, ERpoor
8	Entry age less than 40, ER+/unknown	< 40, ER+/?
9	Entry age 40 - 44, ER+/unknown	40 - 44, ER+/?
10	Entry age 45 - 49, ER+/unknown	45 - 49, ER+/?
11	Entry age 50 - 54, ER+/unknown	50 - 54, ER+/?
12	Entry age 55 - 59, ER+/unknown	55 - 59, ER+/?
13	Entry age 60 - 69, ER+/unknown	60 - 69, ER+/?
14	Entry age 70 or more, ER+/unknown	70+, ER+/?

Regrouping 32 of Entry Age and E.R. Status

-4

	Stratum	Abbreviation
1	Entry age less than 50, ER-poor	< 50, ERpoor
2	Entry age 50 - 59, ER-poor	50 - 59, ERpoor
3	Entry age 60 - 69, ER-poor	60 - 69, ERpoor
4	Entry age 70 or more, ER-poor	70+, ERpoor
5	Entry age less than 50, ER+/unknown	< 50, ER+/?
6	Entry age 50 - 59, ER+/unknown	50 - 59, ER+/?
7	Entry age 60 - 69, ER+/unknown	60 - 69, ER+/?
8	Entry age 70 or more, ER+/unknown	70+, ER+/?

Regrouping 33 of Entry Age and E.R. Status

-5

	Stratum	Abbreviation
1	Entry age less than 40, ER-poor	< 40, ERpoor
2	Entry age 40 - 49, ER-poor	40 - 49, ERpoor
3	Entry age 50 - 59, ER-poor	50 - 59, ERpoor
4	Entry age 60 - 69, ER-poor	60 - 69, ERpoor
5	Entry age 70 or more, ER-poor	70+, ERpoor
6	Entry age less than 40, ER+/unknown	< 40, ER+/?
7	Entry age 40 - 49, ER+/unknown	40 - 49, ER+/?
8	Entry age 50 - 59, ER+/unknown	50 - 59, ER+/?
9	Entry age 60 - 69, ER+/unknown	60 - 69, ER+/?
10	Entry age 70 or more, ER+/unknown	70+, ER+/?

Regrouping 34 of Entry Age and E.R. Status

-6

	Stratum	Abbreviation
1	Entry age less than 50, ER-poor	< 50, ERpoor
2	Entry age 50 - 59, ER-poor	50 - 59, ERpoor
3	Entry age 60 - 69, ER-poor	60 - 69, ERpoor
4	Entry age 70 or more, ER-poor	70+, ERpoor
5	Entry age less than 50, ER unknown	< 50, ER?
6	Entry age 50 - 59, ER unknown	50 - 59, ER?
7	Entry age 60 - 69, ER unknown	60 - 69, ER?
8	Entry age 70 or more, ER unknown	70+, ER?
9	Entry age less than 50, ER+	< 50, ER+
10	Entry age 50 - 59, ER+	50 - 59, ER+
11	Entry age 60 - 69, ER+	60 - 69, ER+
12	Entry age 70 or more, ER+	70+, ER+

Regrouping 35 of Entry Age and E.R. Status

-7

	Stratum	Abbreviation
1	Entry age less than 40, ER-poor	< 40, ERpoor
2	Entry age 40 - 49, ER-poor	40 - 49, ERpoor
3	Entry age 50 - 59, ER-poor	50 - 59, ERpoor
4	Entry age 60 - 69, ER-poor	60 - 69, ERpoor
5	Entry age 70 or more, ER-poor	70+, ERpoor
6	Entry age less than 40, ER unknown	< 40, ER?
7	Entry age 40 - 49, ER unknown	40 - 49, ER?
8	Entry age 50 - 59, ER unknown	50 - 59, ER?
9	Entry age 60 - 69, ER unknwon	60 - 69, ER?
10	Entry age 70 or more, ER unknown	70+, ER?
11	Entry age less than 40, ER+	< 40, ER+
12	Entry age 40 - 49, ER+	40 - 49, ER+
13	Entry age 50 - 59, ER+	50 - 59, ER+
14	Entry age 60 - 69, ER+	60 - 69, ER+
15	Entry age 70 or more, ER+	70+, ER+

E.R. and P.R. Status

	Stratum	Abbreviation
1	ER-poor, PR-poor, entry age less than 50	ERpoor PRpoor < 50
2	ER-poor, PR unknown, entry age less than 50	ERpoor PR? < 50
3	ER-poor, PR+, entry age less than 50	ERpoor PR+ < 50
4	ER unknown, PR-poor, entry age less than 50	ER? PRpoor < 50
5	ER unknown, PR unknown, entry age less than 50	ER? PR? < 50
6	ER unknown, PR+, entry age less than 50	ER? PR+ < 50
7	ER+, PR-poor, entry age less than 50	ER+ PRpoor < 50
8	ER+, PR unknown, entry age less than 50	ER+ PR? < 50
9	ER+, PR+, entry age less than 50	ER+ PR+ < 50
10	ER-poor, PR-poor, entry age 50 or more	ERpoor PRpoor 50+
11	ER-poor, PR unknown, entry age 50 or more	ERpoor PR? 50+
12	ER-poor, PR+, entry age 50 or more	ERpoor PR+ 50+
13	ER unknown, PR-poor, entry age 50 or more	ER? PRpoor 50+
14	ER unknown, PR unknown, entry age 50 or more	ER? PR? 50+
15	ER unknown, PR+, entry age 50 or more	ER? PR+ 50+
16	ER+, PR-poor, entry age 50 or more	ER+ PRpoor 50+
17	ER+, PR unknown, entry age 50 or more	ER+ PR? 50+
18	ER+, PR+, entry age 50 or more	ER+ PR+ 50+

Regrouping 26 of E.R. and P.R. Status

-1

	Stratum	Abbreviation
1	ER-poor, PR-poor	ERpoor PRpoor
2	ER-poor, PR unknown	ERpoor PR?
3	ER-poor, PR+	ERpoor PR+
4	ER unknown, PR-poor	ER? PRpoor
5	ER unknown, PR unknown	ER? PR?
6	ER unknown, PR+	ER? PR+
7	ER+, PR-poor	ER+ PRpoor
8	ER+, PR unknown	ER+ PR?
9	ER+, PR+	ER+ PR+

Regrouping 27 of E.R. and P.R. Status

-5

	Stratum	Abbreviation
1	ER-poor, PR-poor	ERpoor PRpoor
2	ER-poor, PR+/unknown	ERpoor PR+/?
3	ER+/unknown, PR-poor	ER+/? PRpoor
4	ER+/unknown, PR+/unknown	ER+/? PR+/?

E.R. and Menop. Status

	Stratum	Abbreviation
1	ER-poor, all menopausal status, entry age less than 40	ERpoor < 40
2	ER-poor, pre- and perimenop., entry age 40 - 49	ERpoorPre/Peri 40-49
3	ER-poor, postmenopausal, entry age 40 - 49	ERpoor Post 40-49
4	ER-poor, pre- and perimenop., entry age 50 - 59	ERpoorPre/Peri 50-59
5	ER-poor, postmenopausal, entry age 50 - 59	ERpoor Post 50-59
6	ER-poor, all menopausal status, entry age 60 - 69	ERpoor 60-69
7	ER-poor, all menop. status, entry age 70 or more	ERpoor 70+
8	ER+/unknown, all menop. status, entry less than 40	ER+/? < 40
9	ER+/unkn., pre- and perimenop., entry age 40 - 49	ER+/? Pre/Peri 40-49
10	ER+/unknown, postmenopausal, entry age 40 - 49	ER+/? Post 40-49
11	ER+/unkn., pre- and perimenop., entry age 50 - 59	ER+/? Pre/Peri 50-59
12	ER+/unknown, postmenopausal, entry age 50 - 59	ER+/? Post 50-59
13	ER+/unknown, all menop. status, entry age 60 - 69	ER+/? 60-69
14	ER+/unkn., all menop. status, entry age 70 or more	ER+/? 70+

Entry Age

	Stratum	Abbreviation
1	Entry age less than 40	Age < 40
2	Entry age 40 - 44	Age 40 - 44
3	Entry age 45 - 49	Age 45 - 49
4	Entry age 50 - 54	Age 50 - 54
5	Entry age 55 - 59	Age 55 - 59
6	Entry age 60 - 69	Age 60 - 69
7	Entry age 70 or more	Age 70+
8	Entry age unknown	Age unknown

E.R. and Menop. Status

	Stratum	Abbreviation
1	ER-poor, pre- and peri-, entry age less than 50	ERpoor Pre/Peri < 50
2	ER-poor, postmenopausal, entry age less than 50	ERpoor Post < 50
3	ER-poor, pre- and perimenop., entry age 50 - 59	ERpoorPre/Peri 50-59
4	ER-poor, postmenopausal, entry age 50 - 59	ERpoor Post 50-59
5	ER-poor, all menopausal status, entry age 60 - 69	ERpoor 60-69
6	ER-poor, all menop. status, entry age 70 or more	ERpoor 70+
7	ER+/unkn., pre- and peri-, entry age less than 50	ER+/? Pre/Peri < 50
8	ER+/unknown, postmenop., entry age less than 50	ER+/? Post < 50
9	ER+/unkn., pre- and perimenop., entry age 50 - 59	ER+/? Pre/Peri 50-59
10	ER+/unknown, postmenopausal, entry age 50 - 59	ER+/? Post 50-59
11	ER+/unknown, all menop. status, entry age 60 - 69	ER+/? 60-69
12	ER+/unkn., all menop. status, entry age 70 or more	ER+/? 70+

Nodal Status and Entry Age

	Stratum	Abbreviation
1	N0 clearance, entry age less than 40	N0 clear < 40
2	N+ clearance, entry age less than 40	N+ clear < 40
3	N- sampling/clinical, entry age less than 40	N- sam/clin < 40
4	N+ sampling/clinical, entry age less than 40	N+ sam/clin < 40
5	N unknown, entry age less than 40	N? < 40
6	N0 clearance, entry age 40 - 49	N0 clear 40-49
7	N+ clearance, entry age 40 - 49	N+ clear 40-49
8	N- sampling/clinical, entry age 40 - 49	N- sam/clin 40-49
9	N+ sampling/clinical, entry age 40 - 49	N+ sam/clin 40-49
10	N unknown, entry age 40 - 49	N? 40-49
11	N0 clearance, entry age 50 - 59	N0 clear 50-59
12	N+ clearance, entry age 50 - 59	N+ clear 50-59
13	N- sampling/clinical, entry age 50 - 59	N- sam/clin 50-59
14	N+ sampling/clinical, entry age 50 - 59	N+ sam/clin 50-59
15	N unknown, entry age 50 - 59	N? 50-59
16	N0 clearance, entry age 60 - 69	N0 clear 60-69
17	N+ clearance, entry age 60 - 69	N+ clear 60-69
18	N- sampling/clinical, entry age 60 - 69	N- sam/clin 60-69
19	N+ sampling/clinical, entry age 60 - 69	N+ sam/clin 60-69
20	N unknown, entry age 60 - 69	N? 60-69
21	N0 clearance, entry age 70 or more	N0 clear 70+
22	N+ clearance, entry age 70 or more	N+ clear 70+
23	N- sampling/clinical, entry age 70 or more	N- sam/clin 70+
24	N+ sampling/clinical, entry age 70 or more	N+ sam/clin 70+
25	N unknown, entry age 70 or more	N? 70+
26	N0 clearance, entry age unknown	N0 clear Age ?
27	N+ clearance, entry age unknown	N+ clear Age ?
28	N- sampling/clinical, entry age unknown	N- sam/clin Age ?
29	N+ sampling/clinical, entry age unknown	N+ sam/clin Age ?
30	N unknown, entry age unknown	N? Age ?

Entry Age, Nodal & E.R. Status

ANE

	Stratum	Abbreviation
1	N0/N-, ER-poor, entry age less than 50	N0/N- ERpoor < 50
2	N0/N-, ER unknown, entry age less than 50	N0/N- ER? < 50
3	N0/N-, ER+, entry age less than 50	N0/N- ER+ < 50
4	N+/N?, ER-poor, entry age less than 50	N+/N? ERpoor < 50
5	N+/N?, ER unknown, entry age less than 50	N+/N? ER? < 50
6	N+/N?, ER+, entry age less than 50	N+/N? ER+ < 50
7	N0/N-, ER-poor, entry age 50 - 59	N0/N- ERpoor 50-59
8	N0/N-, ER unknown, entry age 50 - 59	N0/N- ER? 50-59
9	N0/N-, ER+, entry age 50 - 59	N0/N- ER+ 50-59
10	N+/N?, ER-poor, entry age 50 - 59	N+/N? ERpoor 50-59
11	N+/N?, ER unknown, entry age 50 - 59	N+/N? ER? 50-59
12	N+/N?, ER+, entry age 50 - 59	N+/N? ER+ 50-59
13	N0/N-, ER-poor, entry age 60 - 69	N0/N- ERpoor 60-69
14	N0/N-, ER unknown, entry age 60 - 69	N0/N- ER? 60-69
15	N0/N-, ER+, entry age 60 - 69	N0/N- ER+ 60-69
16	N+/N?, ER-poor, entry age 60 - 69	N+/N? ERpoor 60-69
17	N+/N?, ER unknown, entry age 60 - 69	N+/N? ER? 60-69
18	N+/N?, ER+, entry age 60 - 69	N+/N? ER+ 60-69
19	N0/N-, ER-poor, entry age 70 or more	N0/N- ERpoor 70+
20	N0/N-, ER unknown, entry age 70 or more	N0/N- ER? 70+
21	N0/N-, ER+, entry age 70 or more	N0/N- ER+ 70+
22	N+/N?, ER-poor, entry age 70 or more	N+/N? ERpoor 70+
23	N+/N?, ER unknown, entry age 70 or more	N+/N? ER? 70+
24	N+/N?, ER+, entry age 70 or more	N+/N? ER+ 70+

Regrouping 38 of Entry Age, Nodal & E.R. Status

-3

	Stratum	Abbreviation
1	N0/N-, ER-poor, entry age less than 50	N0/N- ERpoor < 50
2	N0/N-, ER+/unknown, entry age less than 50	N0/N- ER+/? < 50
3	N+/N?, ER-poor, entry age less than 50	N+/N? ERpoor < 50
4	N+/N?, ER+/unknown, entry age less than 50	N+/N? ER+/? < 50
5	N0/N-, ER-poor, entry age 50 - 59	N0/N- ERpoor 50-59
6	N0/N-, ER+/unknown, entry age 50 - 59	N0/N- ER+/? 50-59
7	N+/N?, ER-poor, entry age 50 - 59	N+/N? ERpoor 50-59
8	N+/N?, ER+/unknown, entry age 50 - 59	N+/N? ER+/? 50-59
9	N0/N-, ER-poor, entry age 60 - 69	N0/N- ERpoor 60-69
10	N0/N-, ER+/unknown, entry age 60 - 69	N0/N- ER+/? 60-69
11	N+/N?, ER-poor, entry age 60 - 69	N+/N? ERpoor 60-69
12	N+/N?, ER+/unknown, entry age 60 - 69	N+/N? ER+/? 60-69
13	N0/N-, ER-poor, entry age 70 or more	N0/N- ERpoor 70+
14	N0/N-, ER+/unknown, entry age 70 or more	N0/N- ER+/? 70+
15	N+/N?, ER-poor, entry age 70 or more	N+/N? ERpoor 70+
16	N+/N?, ER+/unknown, entry age 70 or more	N+/N? ER+/? 70+

Regrouping 45 of Entry Age, Nodal & E.R. Status

-4

	Stratum	Abbreviation
1	N0/N-, ER-poor, entry age less than 50	N0/N- ERpoor < 50
2	N0/N-, ER+/unknown, entry age less than 50	N0/N- ER+/? < 50
3	N+/N?, ER-poor, entry age less than 50	N+/N? ERpoor < 50
4	N+/N?, ER+/unknown, entry age less than 50	N+/N? ER+/? < 50
5	N0/N-, ER-poor, entry age 50 - 69	N0/N- ERpoor 50-69
6	N0/N-, ER+/unknown, entry age 50 - 69	N0/N- ER+/? 50-69
7	N+/N?, ER-poor, entry age 50 - 69	N+/N? ERpoor 50-69
8	N+/N?, ER+/unknown, entry age 50 - 69	N+/N? ER+/? 50-69
9	N0/N-, ER-poor, entry age 70 or more	N0/N- ERpoor 70+
10	N0/N-, ER+/unknown, entry age 70 or more	N0/N- ER+/? 70+
11	N+/N?, ER-poor, entry age 70 or more	N+/N? ERpoor 70+
12	N+/N?, ER+/unknown, entry age 70 or more	N+/N? ER+/? 70+

Regrouping 46 of Entry Age, Nodal & E.R. Status

-5

	Stratum	Abbreviation
1	N0/N-, ER-poor, entry age less than 50	N0/N- ERpoor < 50
2	N0/N-, ER unknown, entry age less than 50	N0/N- ER? < 50
3	N0/N-, ER+, entry age less than 50	N0/N- ER+ < 50
4	N+/N?, ER-poor, entry age less than 50	N+/N? ERpoor < 50
5	N+/N?, ER unknown, entry age less than 50	N+/N? ER? < 50
6	N+/N?, ER+, entry age less than 50	N+/N? ER+ < 50
7	N0/N-, ER-poor, entry age 50 - 69	N0/N- ERpoor 50-69
8	N0/N-, ER unknown, entry age 50 - 69	N0/N- ER? 50-69
9	N0/N-, ER+, entry age 50 - 69	N0/N- ER+ 50-69
10	N+/N?, ER-poor, entry age 50 - 69	N+/N? ERpoor 50-69
11	N+/N?, ER unknown, entry age 50 - 69	N+/N? ER? 50-69
12	N+/N?, ER+, entry age 50 - 69	N+/N? ER+ 50-69
13	N0/N-, ER-poor, entry age 70 or more	N0/N- ERpoor 70+
14	N0/N-, ER unknown, entry age 70 or more	N0/N- ER? 70+
15	N0/N-, ER+, entry age 70 or more	N0/N- ER+ 70+
16	N+/N?, ER-poor, entry age 70 or more	N+/N? ERpoor 70+
17	N+/N?, ER unknown, entry age 70 or more	N+/N? ER? 70+
18	N+/N?, ER+, entry age 70 or more	N+/N? ER+ 70+

Regrouping 57 of Entry Age, Nodal & E.R. Status

-6

	Stratum	Abbreviation
1	ER-poor, entry age less than 50	ERpoor, < 50
2	ER-poor, entry age 50 - 59	ERpoor, 50-59
3	ER-poor, entry age 60 - 69	ERpoor, 60-69
4	ER-poor, entry age 70 or more	ERpoor, 70+
5	ER+/unknown, entry age less than 50	ER+/?, < 50
6	ER+/unknown, entry age 50 - 59	ER+/?, 50-59
7	ER+/unknown, entry age 60 - 69	ER+/?, 60-69
8	ER+/unknown, entry age 70 or more	ER+/?, 70+

Regrouping 58 of Entry Age, Nodal & E.R. Status

-7

	Stratum	Abbreviation
1	ER-poor, entry age less than 50	ERpoor, < 50
2	ER unknown, entry age less than 50	ER?, < 50
3	ER+, entry age less than 50	ER+, < 50
4	ER-poor, entry age 50 - 59	ERpoor, 50-59
5	ER unknown, entry age 50 - 59	ER?, 50-59
6	ER+, entry age 50 - 59	ER+, 50-59
7	ER-poor, entry age 60 - 69	ERpoor, 60-69
8	ER unknown, entry age 60 - 69	ER?, 60-69
9	ER+, entry age 60 - 69	ER+, 60-69
10	ER-poor, entry age 70 or more	ERpoor, 70+
11	ER unknown, entry age 70 or more	ER?, 70+
12	ER+, entry age 70 or more	ER+, 70+

Regrouping 62 of Entry Age, Nodal & E.R. Status

-8

	Stratum	Abbreviation
1	ER-poor, entry age less than 50	ERpoor, < 50
2	ER unknown, entry age less than 50	ER?, < 50
3	ER+, entry age less than 50	ER+, < 50
4	ER-poor, entry age 50 - 69	ERpoor, 50-69
5	ER unknown, entry age 50 - 69	ER?, 50-69
6	ER+, entry age 50 - 69	ER+, 50-69
7	ER-poor, entry age 70 or more	ERpoor, 70+
8	ER unknown, entry age 70 or more	ER?, 70+
9	ER+, entry age 70 or more	ER+, 70+

Entry Age and E.R. Status

	Stratum	Abbreviation
1	Entry age less than 50, ER-poor	< 50, ERpoor
2	Entry age 50 - 69, ER-poor	50 - 69, ERpoor
3	Entry age 70 or more, ER-poor	70+, ERpoor
4	Entry age less than 50, ER unknown	< 50, ER?
5	Entry age 50 - 69, ER unknown	50 - 69, ER?
6	Entry age 70 or more, ER unknown	70+, ER?
7	Entry age less than 50, ER+	< 50, ER+
8	Entry age 50 - 69, ER+	50 - 69, ER+
9	Entry age 70 or more, ER+	70+, ER+
10	Entry age less than 50, ER++	< 50, ER++
11	Entry age 50 - 69, ER++	50 - 69, ER++
12	Entry age 70 or more, ER++	70+, ER++

Regrouping 43 of Entry Age and E.R. Status

-2

	Stratum	Abbreviation
1	Entry age less than 50, ER-poor	< 50, ERpoor
2	Entry age 50 - 69, ER-poor	50 - 69, ERpoor
3	Entry age 70 or more, ER-poor	70+, ERpoor
4	Entry age less than 50, ER+/unknown	< 50, ER+/?
5	Entry age 50 - 69, ER+/unknown	50 - 69, ER+/?
6	Entry age 70 or more, ER+/unknown	70+, ER+/?

Regrouping 44 of Entry Age and E.R. Status

-3

	Stratum	Abbreviation
1	Entry age less than 50, ER-poor	< 50, ERpoor
2	Entry age 50 - 69, ER-poor	50 - 69, ERpoor
3	Entry age 70 or more, ER-poor	70+, ERpoor
4	Entry age less than 50, ER unknown	< 50, ER?
5	Entry age 50 - 69, ER unknown	50 - 69, ER?
6	Entry age 70 or more, ER unknown	70+, ER?
7	Entry age less than 50, ER+/ER++	< 50, ER+/++
8	Entry age 50 - 69, ER+/ER++	50 - 69, ER+/++
9	Entry age 70 or more, ER+/ER++	70+, ER+/++

Entry Age and Menop. Status

	Stratum	Abbreviation
1	Pre- and perimenopausal, entry age less than 50	Pre/Peri < 50
2	Postmenopausal, entry age less than 50	Post < 50
3	Pre- and perimenopausal, entry age 50 - 69	Pre/Peri 50-69
4	Postmenopausal, entry age 50 - 69	Post 50-69
5	All menopausal status, entry age 70 or more	All 70+

Entry Age

	Stratum	Abbreviation
1	Entry age less than 30	Age < 30
2	Entry age 30 - 34	Age 30 - 34
3	Entry age 35 - 39	Age 35 - 39
4	Entry age 40 - 44	Age 40 - 44
5	Entry age 45 - 49	Age 45 - 49
6	Entry age 50 - 54	Age 50 - 54
7	Entry age 55 - 59	Age 55 - 59
8	Entry age 60 - 64	Age 60 - 64
9	Entry age 65 - 69	Age 65 - 69
10	Entry age 70 - 74	Age 70 - 74
11	Entry age 75 - 79	Age 75 - 79
12	Entry age 80 or more	Age 80+
13	Entry age unknown	Age unknown

Primary Tumour Laterality

	Stratum	Abbreviation
1	Left-sided primary, entry age less than 50	Left, < 50
2	Right-sided primary, entry age less than 50	Right, < 50
3	Bilateral primaries, entry age less than 50	Bilateral, < 50
4	Primary laterality unknown, entry age less than 50	Side ?, < 50
5	Left-sided primary, entry age 50 or more	Left, 50+
6	Right-sided primary, entry age 50 or more	Right, 50+
7	Bilateral primaries, entry age 50 or more	Bilateral, 50+
8	Primary laterality unknown, entry age 50 or more	Side ?, 50+

Regrouping 49 of Primary Tumour Laterality

-1

	Stratum	Abbreviation
1	Left-sided primary	Left
2	Right-sided primary	Right
3	Bilateral primaries	Bilateral
4	Primary laterality unknown	Side unknown

Primary Tumour Grade

	Stratum	Abbreviation
1	Well-differentiated, entry age less than 50	Well, < 50
2	Moderately-differentiated, entry age less than 50	Moderate, < 50
3	Poorly-differentiated, entry age less than 50	Poor, < 50
4	Primary grade unknown, entry age less than 50	Grade ?, < 50
5	Well-differentiated, entry age 50 or more	Well, 50+
6	Moderately-differentiated, entry age 50 or more	Moderate, 50+
7	Poorly-differentiated, entry age 50 or more	Poor, 50+
8	Primary grade unknown, entry age 50 or more	Grade ?, 50+

Regrouping 50 of Primary Tumour Grade

-1

	Stratum	Abbreviation
1	Well-differentiated primary	Well-differentiated
2	Moderately-differentiated primary	Moderately-diff.
3	Poorly-differentiated primary	Poorly-diff.
4	Primary grade unknown	Grade unknown

Entry Age and Nodal Status

AN3

	Stratum	Abbreviation
1	Entry age less than 50, N0/N-	< 50, N0/N-
2	Entry age 50 or more, N0/N-	50+, N0/N-
3	Entry age less than 50, N+/N?	< 50, N+/N?
4	Entry age 50 or more, N+/N?	50+, N+/N?

Entry Age, Nodal & E.R. Status

ANE2

	Stratum	Abbreviation
1	N0/N-, ER-poor, entry age less than 50	N0/N- ERpoor < 50
2	N0/N-, ER unknown, entry age less than 50	N0/N- ER? < 50
3	N0/N-, ER+, entry age less than 50	N0/N- ER+ < 50
4	N0/N-, ER++, entry age less than 50	N0/N- ER++ < 50
5	N+/N?, ER-poor, entry age less than 50	N+/N? ERpoor < 50
6	N+/N?, ER unknown, entry age less than 50	N+/N? ER? < 50
7	N+/N?, ER+, entry age less than 50	N+/N? ER+ < 50
8	N+/N?, ER++, entry age less than 50	N+/N? ER++ < 50
9	N0/N-, ER-poor, entry age 50 or more	N0/N- ERpoor 50+
10	N0/N-, ER unknown, entry age 50 or more	N0/N- ER? 50+
11	N0/N-, ER+, entry age 50 or more	N0/N- ER+ 50+
12	N0/N-, ER++, entry age 50 or more	N0/N- ER++ 50+
13	N+/N?, ER-poor, entry age 50 or more	N+/N? ERpoor 50+
14	N+/N?, ER unknown, entry age 50 or more	N+/N? ER? 50+
15	N+/N?, ER+, entry age 50 or more	N+/N? ER+ 50+
16	N+/N?, ER++, entry age 50 or more	N+/N? ER++ 50+

Regrouping 51 of Entry Age, Nodal & E.R. Status

-5

	Stratum	Abbreviation
1	ER-poor	ERpoor
2	ER+/unknown	ER+/?

Regrouping 65 of Entry Age, Nodal & E.R. Status

-6

	Stratum	Abbreviation
1	ER-poor	ERpoor
2	ER unknown	ER?
3	ER+	ER+
4	ER++	ER++

Regrouping 66 of Entry Age, Nodal & E.R. Status

-7

	Stratum	Abbreviation
1	ER-poor	ERpoor
2	ER unknown	ER?
3	ER+	ER+

Age, Nodal Status & Laterality

ANL

	Stratum	Abbreviation
1	Left-sided primary, entry age less than 50, N0/N-	Left, < 50, N0/N-
2	Left-sided primary, entry age less than 50, N+/N?	Left, < 50, N+/N?
3	Right-sided primary, entry age less than 50, N0/N-	Right, < 50, N0/N-
4	Right-sided primary, entry age less than 50, N+/N?	Right, < 50, N+/N?
5	Bilateral primaries, age less than 50, N0/N-	Both, < 50, N0/N-
6	Bilateral primaries, age less than 50, N+/N?	Both, < 50, N+/N?
7	Primary laterality unkn., entry age less than 50, N0/N-	Side ?, < 50, N0/N-
8	Primary laterality unkn., entry age less than 50, N+/N?	Side ?, < 50, N+/N?
9	Left-sided primary, entry age 50 or more, N0/N-	Left, 50+, N0/N-
10	Left-sided primary, entry age 50 or more, N+/N?	Left, 50+, N+/N?
11	Right-sided primary, entry age 50 or more, N0/N-	Right, 50+, N0/N-
12	Right-sided primary, entry age 50 or more, N+/N?	Right, 50+, N+/N?
13	Bilateral primaries, entry age 50 or more, N0/N-	Both, 50+, N0/N-
14	Bilateral primaries, entry age 50 or more, N+/N?	Both, 50+, N+/N?
15	Primary laterality unkn., entry age 50 or more, N0/N-	Side ?, 50+, N0/N-
16	Primary laterality unkn., entry age 50 or more, N+/N?	Side ?, 50+, N+/N?

Regrouping 52 of Age, Nodal Status & Laterality

-5

	Stratum	Abbreviation
1	Left-sided primary	Left
2	Right-sided primary	Right
3	Bilateral primaries	Bilateral
4	Primary laterality unknown	Side unknown

Entry Age, Menop./Nodal Status

ANM

	Stratum	Abbreviation
1	Pre- and perimenop., entry age less than 50, N0/N-	Pre/Peri < 50 N0/N-
2	Postmenopausal, entry age less than 50, N0/N-	Post < 50 N0/N-
3	Pre- and perimenopausal, entry age 50 - 69, N0/N-	Pre/Peri 50-69 N0/N-
4	Postmenopausal, entry age 50 - 69, N0/N-	Post 50-69 N0/N-
5	All menopausal status, entry age 70 or more, N0/N-	All 70+ N0/N-
6	Pre- and perimenop., entry age less than 50, N+/N?	Pre/Peri < 50 N+/N?
7	Postmenopausal, entry age less than 50, N+/N?	Post < 50 N+/N?
8	Pre- and perimenopausal, entry age 50 - 69, N+/N?	Pre/Peri 50-69 N+/N?
9	Postmenopausal, entry age 50 - 69, N+/N?	Post 50-69 N+/N?
10	All menopausal status, entry age 70 or more, N+/N?	All 70+ N+/N?

Regrouping 59 of Entry Age, Menop./Nodal Status

-2

	Stratum	Abbreviation
1	Pre- and perimenopausal, entry age less than 50	Pre/Peri < 50
2	Postmenopausal, entry age less than 50	Post < 50
3	Pre- and perimenopausal, entry age 50 - 69	Pre/Peri 50-69
4	Postmenopausal, entry age 50 - 69	Post 50-69
5	All menopausal status, entry age 70 or more	All 70+

Tumour Size, Age & Nodal Stat.

ATN

	Stratum	Abbreviation
1	T1, entry age less than 50, N0/N-	T1, < 50, N0/N-
2	T1, entry age 50 or more, N0/N-	T1, 50+, N0/N-
3	T1, entry age less than 50, N+/N?	T1, < 50, N+/N?
4	T1, entry age 50 or more, N+/N?	T1, 50+, N+/N?
5	T2, entry age less than 50, N0/N-	T2, < 50, N0/N-
6	T2, entry age 50 or more, N0/N-	T2, 50+, N0/N-
7	T2, entry age less than 50, N+/N?	T2, < 50, N+/N?
8	T2, entry age 50 or more, N+/N?	T2, 50+, N+/N?
9	T3, entry age less than 50, N0/N-	T3, < 50, N0/N-
10	T3, entry age 50 or more, N0/N-	T3, 50+, N0/N-
11	T3, entry age less than 50, N+/N?	T3, < 50, N+/N?
12	T3, entry age 50 or more, N+/N?	T3, 50+, N+/N?
13	T3+ / T4, entry age less than 50, N0/N-	T3+/T4, < 50, N0/N-
14	T3+ / T4, entry age 50 or more, N0/N-	T3+/T4, 50+, N0/N-
15	T3+ / T4, entry age less than 50, N+/N?	T3+/T4, < 50, N+/N?
16	T3+ / T4, entry age 50 or more, N+/N?	T3+/T4, 50+, N+/N?
17	Other / unknown size, entry less than 50, N0/N-	Other/?, < 50, N0/N-
18	Other / unknown size, entry age 50 or more, N0/N-	Other/?, 50+, N0/N-
19	Other / unknown size, entry less than 50, N+/N?	Other/?, < 50, N+/N?
20	Other / unknown size, entry age 50 or more, N+/N?	Other/?, 50+, N+/N?

Regrouping 79 of Tumour Size, Age & Nodal Stat.

-1

	Stratum	Abbreviation
1	N0/N-, 1 - 20 mm (T1)	N0/N- 1-20mm (T1)
2	N0/N-, 21 - 50 mm (T2)	N0/N- 21-50mm (T2)
3	N0/N-, 51 - 100 mm (T3)	N0/N- 51-100mm (T3)
4	N0/N-, > 100 mm (T3+/T4)	N0/N- >100mm, T3+/T4
5	N0/N-, other / unknown size	N0/N- other/size ?
6	N+/N?, 1 - 20 mm (T1)	N+/N? 1-20mm (T1)
7	N+/N?, 21 - 50 mm (T2)	N+/N? 21-50mm (T2)
8	N+/N?, 51 - 100 mm (T3)	N+/N? 51-100mm (T3)
9	N+/N?, > 100 mm (T3+/T4)	N+/N? >100mm, T3+/T4
10	N+/N?, other / unknown size	N+/N? other/size ?

Regrouping 82 of Tumour Size, Age & Nodal Stat.

-3

	Stratum	Abbreviation
1	1 - 20 mm (T1), entry age less than 50	1-20mm (T1) , < 50
2	21 - 50 mm (T2) , entry age less than 50	21-50mm (T2), < 50
3	51 - 100 mm (T3) , entry age less than 50	51-100mm (T3) , < 50
4	> 100 mm (T3+/T4), entry age less than 50	>100mm, T3+/T4 , < 50
5	Other / unknown size, entry age less than 50	Other / size ?, < 50
6	1 - 20 mm (T1), entry age 50 or more	1-20mm (T1), 50+
7	21 - 50 mm (T2), entry age 50 or more	21-50mm (T2), 50+
8	51 - 100 mm (T3), entry age 50 or more	51-100mm (T3), 50+
9	> 100 mm (T3+/T4), entry age 50 or more	>100mm, T3+/T4, 50+
10	Other / unknown size, entry age 50 or more	Other / size ?, 50+

Regrouping 61 of Tumour Size, Age & Nodal Stat.

-5

	Stratum	Abbreviation
1	1 - 20 mm (T1)	1 - 20 mm (T1)
2	21 - 50 mm (T2)	21 - 50 mm (T2)
3	51 - 100 mm (T3)	51 - 100 mm (T3)
4	> 100 mm (T3+/T4)	> 100 mm (T3+/T4)
5	Other / unknown size	Other / unknown size

Grade, Age and Nodal Status

ANG

	Stratum	Abbreviation
1	Well-differentiated, entry age less than 50, N0/N-	Well, < 50, N0/N-
2	Moderately-differentiated, entry age less than 50, N0/N-	Moderate, < 50, N0/N-
3	Poorly-differentiated, entry age less than 50, N0/N-	Poor, < 50, N0/N-
4	Primary grade unknown, entry age less than 50, N0/N-	Grade ?, < 50, N0/N-
5	Well-differentiated, entry age less than 50, N+/N?	Well, < 50, N+/N?
6	Moderately-differentiated, entry age less than 50, N+/N?	Moderate, < 50, N+/N?
7	Poorly-differentiated, entry age less than 50, N+/N?	Poor, < 50, N+/N?
8	Primary grade unknown, entry age less than 50, N+/N?	Grade ?, < 50, N+/N?
9	Well-differentiated, entry age 50 or more, N0/N-	Well, 50+, N0/N-
10	Moderately-differentiated, entry age 50 or more, N0/N-	Moderate, 50+, N0/N-
11	Poorly-differentiated, entry age 50 or more, N0/N-	Poor, 50+, N0/N-
12	Primary grade unknown, entry age 50 or more, N0/N-	Grade ?, 50+, N0/N-
13	Well-differentiated, entry age 50 or more, N+/N?	Well, 50+, N+/N?
14	Moderately-differentiated, entry age 50 or more, N+/N?	Moderate, 50+, N+/N?
15	Poorly-differentiated, entry age 50 or more, N+/N?	Poor, 50+, N+/N?
16	Primary grade unknown, entry age 50 or more, N+/N?	Grade ?, 50+, N+/N?

Regrouping 83 of Grade, Age and Nodal Status

-3

	Stratum	Abbreviation
1	Well-differentiated, entry age less than 50	Well-diff., < 50
2	Moderately-differentiated, entry age less than 50	Moderately-diff <50.
3	Poorly-differentiated, entry age less than 50	Poorly-diff., < 50
4	Primary grade unknown, entry age less than 50	Grade ?, < 50
5	Well-differentiated, entry age 50 or more	Well-diff., 50+
6	Moderately-differentiated, entry age 50 or more	Moderately-diff. 50+
7	Poorly-differentiated, entry age 50 or more	Poorly-diff., 50+
8	Primary grade unknown, entry age 50 or more	Grade ?, 50+

Regrouping 64 of Grade, Age and Nodal Status

-5

	Stratum	Abbreviation
1	Well-differentiated primary	Well-differentiated
2	Moderately-differentiated primary	Moderately-diff.
3	Poorly-differentiated primary	Poorly-diff.
4	Primary grade unknown	Grade unknown

Tumour Size, Age & Nodal Stat.

ATN2

	Stratum	Abbreviation
1	T1, entry age less than 50, N0/N-	T1, < 50, N0/N-
2	T1, entry age 50 or more, N0/N-	T1, 50+, N0/N-
3	T1, entry age less than 50, N+/N?	T1, < 50, N+/N?
4	T1, entry age 50 or more, N+/N?	T1, 50+, N+/N?
5	T2, entry age less than 50, N0/N-	T2, < 50, N0/N-
6	T2, entry age 50 or more, N0/N-	T2, 50+, N0/N-
7	T2, entry age less than 50, N+/N?	T2, < 50, N+/N?
8	T2, entry age 50 or more, N+/N?	T2, 50+, N+/N?
9	Other, entry age less than 50, N0/N-	Other, < 50, N0/N-
10	Other, entry age 50 or more, N0/N-	Other, 50+, N0/N-
11	Other, entry age less than 50, N+/N?	Other, < 50, N+/N?
12	Other, entry age 50 or more, N+/N?	Other, 50+, N+/N?
13	Unknown size, entry age less than 50, N0/N-	Size ?, < 50, N0/N-
14	Unknown size, entry age 50 or more, N0/N-	Size ?, 50+, N0/N-
15	Unknown size, entry age less than 50, N+/N?	Size ?, < 50, N+/N?
16	Unknown size, entry age 50 or more, N+/N?	Size ?, 50+, N+/N?

Regrouping 67 of Tumour Size, Age and Nodal Stat.

-5

	Stratum	Abbreviation
1	1 - 20 mm (T1)	1 - 20 mm (T1)
2	21 - 50 mm (T2)	21 - 50 mm (T2)
3	Other	Other
4	Unknown size	Unknown size

Stratification

Mnemonic

Structure

Entry Age, Nodal & E.R. Status

ANE3

	Stratum	Abbreviation
1	N0/N-, ER-poor, entry age less than 30	N0/N- ERpoor < 30
2	N0/N-, ER unknown, entry age less than 30	N0/N- ER? < 30
3	N0/N-, ER+, entry age less than 30	N0/N- ER+ < 30
4	N+/N?, ER-poor, entry age less than 30	N+/N? ERpoor < 30
5	N+/N?, ER unknown, entry age less than 30	N+/N? ER? < 30
6	N+/N?, ER+, entry age less than 30	N+/N? ER+ < 30
7	N0/N-, ER-poor, entry age 30 - 34	N0/N- ERpoor 30-34
8	N0/N-, ER unknown, entry age 30 - 34	N0/N- ER? 30-34
9	N0/N-, ER+, entry age 30 - 34	N0/N- ER+ 30-34
10	N+/N?, ER-poor, entry age 30 - 34	N+/N? ERpoor 30-34
11	N+/N?, ER unknown, entry age 30 - 34	N+/N? ER? 30-34
12	N+/N?, ER+, entry age 30 - 34	N+/N? ER+ 30-34
13	N0/N-, ER-poor, entry age 35 - 39	N0/N- ERpoor 35-39
14	N0/N-, ER unknown, entry age 35 - 39	N0/N- ER? 35-39
15	N0/N-, ER+, entry age 35 - 39	N0/N- ER+ 35-39
16	N+/N?, ER-poor, entry age 35 - 39	N+/N? ERpoor 35-39
17	N+/N?, ER unknown, entry age 35 - 39	N+/N? ER? 35-39
18	N+/N?, ER+, entry age 35 - 39	N+/N? ER+ 35-39
19	N0/N-, ER-poor, entry age 40 - 44	N0/N- ERpoor 40-44
20	N0/N-, ER unknown, entry age 40 - 44	N0/N- ER? 40-44
21	N0/N-, ER+, entry age 40 - 44	N0/N- ER+ 40-44
22	N+/N?, ER-poor, entry age 40 - 44	N+/N? ERpoor 40-44
23	N+/N?, ER unknown, entry age 40 - 44	N+/N? ER? 40-44
24	N+/N?, ER+, entry age 40 - 44	N+/N? ER+ 40-44
25	N0/N-, ER-poor, entry age 45 - 49	N0/N- ERpoor 45-49
26	N0/N-, ER unknown, entry age 45 - 49	N0/N- ER? 45-49
27	N0/N-, ER+, entry age 45 - 49	N0/N- ER+ 45-49
28	N+/N?, ER-poor, entry age 45 - 49	N+/N? ERpoor 45-49
29	N+/N?, ER unknown, entry age 45 - 49	N+/N? ER? 45-49
30	N+/N?, ER+, entry age 45 - 49	N+/N? ER+ 45-49
31	N0/N-, ER-poor, entry age 50 - 54	N0/N- ERpoor 50-54
32	N0/N-, ER unknown, entry age 50 - 54	N0/N- ER? 50-54
33	N0/N-, ER+, entry age 50 - 54	N0/N- ER+ 50-54
34	N+/N?, ER-poor, entry age 50 - 54	N+/N? ERpoor 50-54
35	N+/N?, ER unknown, entry age 50 - 54	N+/N? ER? 50-54
36	N+/N?, ER+, entry age 50 - 54	N+/N? ER+ 50-54
37	N0/N-, ER-poor, entry age 55 - 59	N0/N- ERpoor 55-59
38	N0/N-, ER unknown, entry age 55 - 59	N0/N- ER? 55-59
39	N0/N-, ER+, entry age 55 - 59	N0/N- ER+ 55-59
40	N+/N?, ER-poor, entry age 55 - 59	N+/N? ERpoor 55-59
41	N+/N?, ER unknown, entry age 55 - 59	N+/N? ER? 55-59
42	N+/N?, ER+, entry age 55 - 59	N+/N? ER+ 55-59
43	N0/N-, ER-poor, entry age 60 - 64	N0/N- ERpoor 60-64
44	N0/N-, ER unknown, entry age 60 - 64	N0/N- ER? 60-64
45	N0/N-, ER+, entry age 60 - 64	N0/N- ER+ 60-64
46	N+/N?, ER-poor, entry age 60 - 64	N+/N? ERpoor 60-64
47	N+/N?, ER unknown, entry age 60 - 64	N+/N? ER? 60-64
48	N+/N?, ER+, entry age 60 - 64	N+/N? ER+ 60-64
49	N0/N-, ER-poor, entry age 65 - 69	N0/N- ERpoor 65-69
50	N0/N-, ER unknown, entry age 65 - 69	N0/N- ER? 65-69
51	N0/N-, ER+, entry age 65 - 69	N0/N- ER+ 65-69
52	N+/N?, ER-poor, entry age 65 - 69	N+/N? ERpoor 65-69
53	N+/N?, ER unknown, entry age 65 - 69	N+/N? ER? 65-69
54	N+/N?, ER+, entry age 65 - 69	N+/N? ER+ 65-69
55	N0/N-, ER-poor, entry age 70 - 74	N0/N- ERpoor 70-74
56	N0/N-, ER unknown, entry age 70 - 74	N0/N- ER? 70-74
57	N0/N-, ER+, entry age 70 - 74	N0/N- ER+ 70-74
58	N+/N?, ER-poor, entry age 70 - 74	N+/N? ERpoor 70-74
59	N+/N?, ER unknown, entry age 70 - 74	N+/N? ER? 70-74
60	N+/N?, ER+, entry age 70 - 74	N+/N? ER+ 70-74
61	N0/N-, ER-poor, entry age 75-79	N0/N- ERpoor 75-79
62	N0/N-, ER unknown, entry age 75 - 79	N0/N- ER? 75-79
63	N0/N-, ER+, entry age 75 - 79	N0/N- ER+ 75-79
64	N+/N?, ER-poor, entry age 75-79	N+/N? ERpoor 75-79
65	N+/N?, ER unknown, entry age 75 - 79	N+/N? ER? 75-79
66	N+/N?, ER+, entry age 75 - 79	N+/N? ER+ 75-79
67	N0/N-, ER-poor, entry age 80 or more	N0/N- ERpoor 80+
68	N0/N-, ER unknown, entry age 80 or more	N0/N- ER? 80+
69	N0/N-, ER+, entry age 80 or more	N0/N- ER+ 80+
70	N+/N?, ER-poor, entry age 80 or more	N+/N? ERpoor 80+
71	N+/N?, ER unknown, entry age 80 or more	N+/N? ER? 80+
72	N+/N?, ER+, entry age 80 or more	N+/N? ER+ 80+
73	N0/N-, ER-poor, entry age unknown	N0/N- ERpoor Age?
74	N0/N-, ER unknown, entry age unknown	N0/N- ER? Age?
75	N0/N-, ER+, entry age unknown	N0/N- ER+ Age?
76	N+/N?, ER-poor, entry age unknown	N+/N? ERpoor Age?
77	N+/N?, ER unknown, entry age unknown	N+/N? ER? Age?
78	N+/N?, ER+, entry age unknown	N+/N? ER+ Age?

Regrouping 71 of Entry Age, Nodal & E.R. Status

-3

	Stratum	Abbreviation
1	ER-poor, entry age less than 35	ER-poor, Age < 35
2	ER unknown, entry age less than 35	ER?, Age < 35
3	ER+, entry age less than 35	ER+, Age < 35
4	ER-poor, entry age 35 - 39	ER-poor, Age 35-39
5	ER unknown, entry age 35 - 39	ER?, Age 35-39
6	ER+, entry age 35 - 39	ER+, Age 35-39
7	ER-poor, entry age 40 - 44	ER-poor, Age 40-44
8	ER unknown, entry age 40 - 44	ER?, Age 40-44
9	ER+, entry age 40 - 44	ER+, Age 40-44
10	ER-poor, entry age 45 - 49	ER-poor, Age 45-49
11	ER unknown, entry age 45 - 49	ER?, Age 45-49
12	ER+, entry age 45 - 49	ER+, Age 45-49
13	ER-poor, entry age 50 - 54	ER-poor, Age 50-54
14	ER unknown, entry age 50 - 54	ER?, Age 50-54
15	ER+, entry age 50 - 54	ER+, Age 50-54
16	ER-poor, entry age 55 - 59	ER-poor, Age 55-59
17	ER unknown, entry age 55 - 59	ER?, Age 55-59
18	ER+, entry age 55 - 59	ER+, Age 55-59
19	ER-poor, entry age 60 - 64	ER-poor, Age 60-64
20	ER unknown, entry age 60 - 64	ER?, Age 60-64
21	ER+, entry age 60 - 64	ER+, Age 60-64
22	ER-poor, entry age 65 - 69	ER-poor, Age 65-69
23	ER unknown, entry age 65 - 69	ER?, Age 65-69
24	ER+, entry age 65 - 69	ER+, Age 65-69
25	ER-poor, entry age 70 or more	ER-poor, Age 70+
26	ER unknown, entry age 70 or more	ER?, Age 70+
27	ER+, entry age 70 or more	ER+, Age 70+
28	ER-poor, entry age unknown	ER-poor, Age ?
29	ER unknown, entry age unknown	ER?, Age ?
30	ER+, entry age unknown	ER+, Age ?

Regrouping 72 of Entry Age, Nodal & E.R. Status

-4

	Stratum	Abbreviation
1	Entry age less than 35	Age < 35
2	Entry age 35 - 39	Age 35 - 39
3	Entry age 40 - 44	Age 40 - 44
4	Entry age 45 - 49	Age 45 - 49
5	Entry age 50 - 54	Age 50 - 54
6	Entry age 55 - 59	Age 55 - 59
7	Entry age 60 - 64	Age 60 - 64
8	Entry age 65 - 69	Age 65 - 69
9	Entry age 70 or more	Age 70+
10	Entry age unknown	Age ?

Regrouping 73 of Entry Age, Nodal & E.R. Status

-5

	Stratum	Abbreviation
1	ER-poor, entry age less than 35	ER-poor, Age < 35
2	ER unknown, entry age less than 35	ER?, Age < 35
3	ER+, entry age less than 35	ER+, Age < 35
4	ER-poor, entry age 35 - 39	ER-poor, Age 35-39
5	ER unknown, entry age 35 - 39	ER?, Age 35-39
6	ER+, entry age 35 - 39	ER+, Age 35-39
7	ER-poor, entry age 40 - 49	ER-poor, Age 40-49
8	ER unknown, entry age 40 - 49	ER?, Age 40-49
9	ER+, entry age 40 - 49	ER+, Age 40-49
10	ER-poor, entry age 50 - 59	ER-poor, Age 50-59
11	ER unknown, entry age 50 - 59	ER?, Age 50-59
12	ER+, entry age 50 - 59	ER+, Age 50-59
13	ER-poor, entry age 60 - 69	ER-poor, Age 60-69
14	ER unknown, entry age 60 - 69	ER?, Age 60-69
15	ER+, entry age 60 - 69	ER+, Age 60-69
16	ER-poor, entry age 70 or more	ER-poor, Age 70+
17	ER unknown, entry age 70 or more	ER?, Age 70+
18	ER+, entry age 70 or more	ER+, Age 70+
19	ER-poor, entry age unknown	ER-poor, Age ?
20	ER unknown, entry age unknown	ER?, Age ?
21	ER+, entry age unknown	ER+, Age ?

Regrouping 68 of Entry Age, Nodal & E.R. Status

-7

	Stratum	Abbreviation
1	ER-poor, entry age less than 30	ER-poor, Age < 30
2	ER unknown, entry age less than 30	ER?, Age < 30
3	ER+, entry age less than 30	ER+, Age < 30
4	ER-poor, entry age 30 - 34	ER-poor, Age 30-34
5	ER unknown, entry age 30 - 34	ER?, Age 30-34
6	ER+, entry age 30 - 34	ER+, Age 30-34
7	ER-poor, entry age 35 - 39	ER-poor, Age 35-39
8	ER unknown, entry age 35 - 39	ER?, Age 35-39
9	ER+, entry age 35 - 39	ER+, Age 35-39
10	ER-poor, entry age 40 - 44	ER-poor, Age 40-44
11	ER unknown, entry age 40 - 44	ER?, Age 40-44
12	ER+, entry age 40 - 44	ER+, Age 40-44
13	ER-poor, entry age 45 - 49	ER-poor, Age 45-49
14	ER unknown, entry age 45 - 49	ER?, Age 45-49
15	ER+, entry age 45 - 49	ER+, Age 45-49
16	ER-poor, entry age 50 - 54	ER-poor, Age 50-54
17	ER unknown, entry age 50 - 54	ER?, Age 50-54
18	ER+, entry age 50 - 54	ER+, Age 50-54
19	ER-poor, entry age 55 - 59	ER-poor, Age 55-59
20	ER unknown, entry age 55 - 59	ER?, Age 55-59
21	ER+, entry age 55 - 59	ER+, Age 55-59
22	ER-poor, entry age 60 - 64	ER-poor, Age 60-64
23	ER unknown, entry age 60 - 64	ER?, Age 60-64
24	ER+, entry age 60 - 64	ER+, Age 60-64
25	ER-poor, entry age 65 - 69	ER-poor, Age 65-69
26	ER unknown, entry age 65 - 69	ER?, Age 65-69
27	ER+, entry age 65 - 69	ER+, Age 65-69
28	ER-poor, entry age 70 - 74	ER-poor, Age 70-74
29	ER unknown, entry age 70 - 74	ER?, Age 70-74
30	ER+, entry age 70 - 74	ER+, Age 70-74
31	ER-poor, entry age 75-79	ER-poor, Age 75-79
32	ER unknown, entry age 75 - 79	ER?, Age 75-79
33	ER+, entry age 75 - 79	ER+, Age 75-79
34	ER-poor, entry age 80 or more	ER-poor, Age 80+
35	ER unknown, entry age 80 or more	ER?, Age 80+
36	ER+, entry age 80 or more	ER+, Age 80+
37	ER-poor, entry age unknown	ER-poor, Age ?
38	ER unknown, entry age unknown	ER?, Age ?
39	ER+, entry age unknown	ER+, Age ?

Entry Age, Nodal Status & BED

ANB

	Stratum	Abbreviation
1	N0/N-, entry age less than 50, zero BED	N0/N- < 50 Zero BED
2	N+/N?, entry age less than 50, zero BED	N+/N? < 50 Zero BED
3	N0/N-, entry age less than 50, low BED	N0/N- < 50 Low BED
4	N+/N?, entry age less than 50, low BED	N+/N? < 50 Low BED
5	N0/N-, entry age less than 50, medium BED	N0/N- < 50 Med. BED
6	N+/N?, entry age less than 50, medium BED	N+/N? < 50 Med. BED
7	N0/N-, entry age less than 50, high BED	N0/N- < 50 High BED
8	N+/N?, entry age less than 50, high BED	N+/N? < 50 High BED
9	N0/N-, entry age less than 50, BED unknown	N0/N- < 50 BED ?
10	N+/N?, entry age less than 50, BED unknown	N+/N? < 50 BED ?
11	N0/N-, entry age 50 or more, zero BED	N0/N- 50+ Zero BED
12	N+/N?, entry age 50 or more, zero BED	N+/N? 50+ Zero BED
13	N0/N-, entry age 50 or more, low BED	N0/N- 50+ Low BED
14	N+/N?, entry age 50 or more, low BED	N+/N? 50+ Low BED
15	N0/N-, entry age 50 or more, medium BED	N0/N- 50+ Med. BED
16	N+/N?, entry age 50 or more, medium BED	N+/N? 50+ Med. BED
17	N0/N-, entry age 50 or more, high BED	N0/N- 50+ High BED
18	N+/N?, entry age 50 or more, high BED	N+/N? 50+ High BED
19	N0/N-, entry age 50 or more, BED unknown	N0/N- 50+ BED ?
20	N+/N?, entry age 50 or more, BED unknown	N+/N? 50+ BED ?

Regrouping 69 of Entry Age, Nodal Status & BED

-1

	Stratum	Abbreviation
1	N0/N-, zero BED	N0/N-, Zero BED
2	N+/N?, zero BED	N+/N?, Zero BED
3	N0/N-, low BED	N0/N-, Low BED
4	N+/N?, low BED	N+/N?, Low BED
5	N0/N-, medium BED	N0/N-, Medium BED
6	N+/N?, medium BED	N+/N?, Medium BED
7	N0/N-, high BED	N0/N-, High BED
8	N+/N?, high BED	N+/N?, High BED
9	N0/N-, BED unknown	N0/N-, BED ?
10	N+/N?, BED unknown	N+/N?, BED ?

Regrouping 70 of Entry Age, Nodal Status & BED

-5

	Stratum	Abbreviation
1	Zero BED	Zero BED
2	Low BED	Low BED
3	Medium BED	Medium BED
4	High BED	High BED
5	BED unknown	BED ?

Nodal and E.R. Status

NE4

	Stratum	Abbreviation
1	N0/N-, ER-poor, entry age less than 50	N0/N- ERpoor < 50
2	N0/N-, ER unknown, entry age less than 50	N0/N- ER? < 50
3	N0/N-, ER+, entry age less than 50	N0/N- ER+ < 50
4	N?, ER-poor, entry age less than 50	N? ERpoor < 50
5	N?, ER unknown, entry age less than 50	N? ER? < 50
6	N?, ER+, entry age less than 50	N? ER+ < 50
7	N+, ER-poor, entry age less than 50	N+ ERpoor < 50
8	N+, ER unknown, entry age less than 50	N+ ER? < 50
9	N+, ER+, entry age less than 50	N+ ER+ < 50
10	N0/N-, ER-poor, entry age 50 or more	N0/N- ERpoor 50+
11	N0/N-, ER unknown, entry age 50 or more	N0/N- ER? 50+
12	N0/N-, ER+, entry age 50 or more	N0/N- ER+ 50+
13	N?, ER-poor, entry age 50 or more	N? ERpoor 50+
14	N?, ER unknown, entry age 50 or more	N? ER? 50+
15	N?, ER+, entry age 50 or more	N? ER+ 50+
16	N+, ER-poor, entry age 50 or more	N+ ERpoor 50+
17	N+, ER unknown, entry age 50 or more	N+ ER? 50+
18	N+, ER+, entry age 50 or more	N+ ER+ 50+

Regrouping 75 of Nodal and E.R. Status

-1

	Stratum	Abbreviation
1	N0/N-, ER-poor	N0/N- ER-poor
2	N0/N-, ER unknown	N0/N- ER?
3	N0/N-, ER+	N0/N- ER+
4	N?, ER-poor	N? ER-poor
5	N?, ER unknown	N? ER?
6	N?, ER+	N? ER+
7	N+, ER-poor	N+ ER-poor
8	N+, ER unknown	N+ ER?
9	N+, ER+	N+ ER+

Regrouping 76 of Nodal and E.R. Status

-2

	Stratum	Abbreviation
1	N0/N-, entry age less than 50	N0/N-, < 50
2	N?, entry age less than 50	N?,- < 50
3	N+, entry age less than 50	N+, < 50
4	N0/N-, entry age 50 or more	N0/N-, 50+
5	N?, entry age 50 or more	N?, 50+
6	N+, entry age 50 or more	N+, 50+

Regrouping 74 of Nodal and E.R. Status

-3

	Stratum	Abbreviation
1	N0/N-	N0/N-
2	N?	N?
3	N+	N+

Regrouping 77 of Nodal and E.R. Status

-4

	Stratum	Abbreviation
1	ER-poor, entry age less than 50	ER-poor, < 50
2	ER?, entry age less than 50	ER?,- < 50
3	ER+, entry age less than 50	ER+, < 50
4	ER-poor, entry age 50 or more	ER-poor, 50+
5	ER?, entry age 50 or more	ER?, 50+
6	ER+, entry age 50 or more	ER+, 50+

Tumour, Age, E.R., Nodal Stat.

ATNE

	Stratum	Abbreviation
1	T1, entry age less than 50, N0/N-, ER-poor	T1 < 50 N0/N- ERpoor
2	T1, entry age 50 or more, N0/N-, ER-poor	T1 50+ N0/N- ERpoor
3	T1, entry age less than 50, N+/N?, ER-poor	T1 < 50 N+/N? ERpoor
4	T1, entry age 50 or more, N+/N?, ER-poor	T1 50+ N+/N? ERpoor
5	T2, entry age less than 50, N0/N-, ER-poor	T2 < 50 N0/N- ERpoor
6	T2, entry age 50 or more, N0/N-, ER-poor	T2 50+ N0/N- ERpoor
7	T2, entry age less than 50, N+/N?, ER-poor	T2 < 50 N+/N? ERpoor
8	T2, entry age 50 or more, N+/N?, ER-poor	T2 50+ N+/N? ERpoor
9	T3, entry age less than 50, N0/N-, ER-poor	T3 < 50 N0/N- ERpoor
10	T3, entry age 50 or more, N0/N-, ER-poor	T3 50+ N0/N- ERpoor
11	T3, entry age less than 50, N+/N?, ER-poor	T3 < 50 N+/N? ERpoor
12	T3, entry age 50 or more, N+/N?, ER-poor	T3 50+ N+/N? ERpoor
13	T3+ / T4, entry age less than 50, N0/N-, ER-poor	T3+/T4 <50 N0/N- ERp
14	T3+ / T4, entry age 50 or more, N0/N-, ER-poor	T3+/T4 50+ N0/N- ERp
15	T3+ / T4, entry age less than 50, N+/N?, ER-poor	T3+/T4 <50 N+/N? ERp
16	T3+ / T4, entry age 50 or more, N+/N?, ER-poor	T3+/T4 50+ N+/N? ERp
17	Other / unknown size, entry < 50, N0/N-, ER-poor	Othr/? <50 N0/N- ERp
18	Other / unknown size, entry age 50+, N0/N-, ER-poor	Othr/? 50+ N0/N- ERp
19	Other / unknown size, entry < 50, N+/N?, ER-poor	Othr/? <50 N+/N? ERp
20	Other / unknown size, entry age 50+, N+/N?, ER-poor	Othr/? 50+ N+/N? ERp
21	T1, entry age less than 50, N0/N-, ER unknown	T1 < 50 N0/N- ER?
22	T1, entry age 50 or more, N0/N-, ER unknown	T1 50+ N0/N- ER?
23	T1, entry age less than 50, N+/N?, ER unknown	T1 < 50 N+/N? ER?
24	T1, entry age 50 or more, N+/N?, ER unknown	T1 50+ N+/N? ER?
25	T2, entry age less than 50, N0/N-, ER unknown	T2 < 50 N0/N- ER?
26	T2, entry age 50 or more, N0/N-, ER unknown	T2 50+ N0/N- ER?
27	T2, entry age less than 50, N+/N?, ER unknown	T2 < 50 N+/N? ER?
28	T2, entry age 50 or more, N+/N?, ER unknown	T2 50+ N+/N? ER?
29	T3, entry age less than 50, N0/N-, ER unknown	T3 < 50 N0/N- ER?
30	T3, entry age 50 or more, N0/N-, ER unknown	T3 50+ N0/N- ER?
31	T3, entry age less than 50, N+/N?, ER unknown	T3 < 50 N+/N? ER?
32	T3, entry age 50 or more, N+/N?, ER unknown	T3 50+ N+/N? ER?
33	T3+ / T4, entry age less than 50, N0/N-, ER unkn.	T3+/T4 <50 N0/N- ER?
34	T3+ / T4, entry age 50 or more, N0/N-, ER unknown	T3+/T4 50+ N0/N- ER?
35	T3+ / T4, entry age less than 50, N+/N?, ER unkn.	T3+/T4 <50 N+/N? ER?
36	T3+ / T4, entry age 50 or more, N+/N?, ER unknown	T3+/T4 50+ N+/N? ER?
37	Other / unknown size, entry < 50, N0/N-, ER unkn.	Othr/? <50 N0/N- ER?
38	Other / unknown size, entry 50+, N0/N-, ER unkn.	Othr/? 50+ N0/N- ER?
39	Other / unknown size, entry < 50, N+/N?, ER unkn.	Othr/? <50 N+/N? ER?
40	Other / unknown size, entry 50+, N+/N?, ER unkn.	Othr/? 50+ N+/N? ER?
41	T1, entry age less than 50, N0/N-, ER+	T1 < 50 N0/N- ER+
42	T1, entry age 50 or more, N0/N-, ER+	T1 50+ N0/N- ER+
43	T1, entry age less than 50, N+/N?, ER+	T1 < 50 N+/N? ER+
44	T1, entry age 50 or more, N+/N?, ER+	T1 50+ N+/N? ER+
45	T2, entry age less than 50, N0/N-, ER+	T2 < 50 N0/N- ER+
46	T2, entry age 50 or more, N0/N-, ER+	T2 50+ N0/N- ER+
47	T2, entry age less than 50, N+/N?, ER+	T2 < 50 N+/N? ER+
48	T2, entry age 50 or more, N+/N?, ER+	T2 50+ N+/N? ER+
49	T3, entry age less than 50, N0/N-, ER+	T3 < 50 N0/N- ER+
50	T3, entry age 50 or more, N0/N-, ER+	T3 50+ N0/N- ER+
51	T3, entry age less than 50, N+/N?, ER+	T3 < 50 N+/N? ER+
52	T3, entry age 50 or more, N+/N?, ER+	T3 50+ N+/N? ER+
53	T3+ / T4, entry age less than 50, N0/N-, ER+	T3+/T4 <50 N0/N- ER+
54	T3+ / T4, entry age 50 or more, N0/N-, ER+	T3+/T4 50+ N0/N- ER+
55	T3+ / T4, entry age less than 50, N+/N?, ER+	T3+/T4 <50 N+/N? ER+
56	T3+ / T4, entry age 50 or more, N+/N?, ER+	T3+/T4 50+ N+/N? ER+
57	Other / unknown size, entry age < 50, N0/N-, ER+	Othr/? <50 N0/N- ER+
58	Other / unknown size, entry age 50+, N0/N-, ER+	Othr/? 50+ N0/N- ER+
59	Other / unknown size, entry age < 50, N+/N?, ER+	Othr/? <50 N+/N? ER+
60	Other / unknown size, entry age 50+, N+/N?, ER+	Othr/? 50+ N+/N? ER+

Regrouping 80 of Tumour, Age, E.R., Nodal Stat.

-1

	Stratum	Abbreviation
1	N0/N-, 1 - 20 mm (T1), ER-poor	N0/N- 1-20mm(T1) ERp
2	N0/N-, 21 - 50 mm (T2), ER-poor	N0/N- 21-50mm(T2)ERp
3	N0/N-, 51 - 100 mm (T3), ER-poor	N0/N-51-100mm(T3)ERp
4	N0/N-, > 100 mm (T3+/T4), ER-poor	N0N->100mm(T3+T4)ERp
5	N0/N-, other / unknown size, ER-poor	N0/N- othr/size? ERp
6	N0/N-, 1 - 20 mm (T1), ER unknown	N0/N- 1-20mm(T1) ER?
7	N0/N-, 21 - 50 mm (T2), ER unknown	N0/N- 21-50mm(T2)ER?
8	N0/N-, 51 - 100 mm (T3), ER unknown	N0/N-51-100mm(T3)ER?
9	N0/N-, > 100 mm (T3+/T4), ER unknown	N0N->100mm(T3+T4)ER?
10	N0/N-, other / unknown size, ER unknown	N0/N- othr/size? ER?
11	N0/N-, 1 - 20 mm (T1), ER+	N0/N- 1-20mm(T1) ER+
12	N0/N-, 21 - 50 mm (T2), ER+	N0/N- 21-50mm(T2)ER+
13	N0/N-, 51 - 100 mm (T3), ER+	N0/N-51-100mm(T3)ER+
14	N0/N-, > 100 mm (T3+/T4), ER+	N0N->100mm(T3+T4)ER+
15	N0/N-, other / unknown size, ER+	N0/N- othr/size? ER+
16	N+/N?-, 1 - 20 mm (T1), ER-poor	N+/N? 1-20mm(T1) ERp
17	N+/N?, 21 - 50 mm (T2), ER-poor	N+/N? 21-50mm(T2)ERp
18	N+/N?, 51 - 100 mm (T3), ER-poor	N+/N?51-100mm(T3)ERp
19	N+/N?, > 100 mm (T3+/T4), ER-poor	N+N?>100mm(T3+T4)ERp
20	N+/N?, other / unknown size, ER-poor	N+/N? othr/size? ERp
21	N+/N?, 1 - 20 mm (T1), ER unknown	N+/N? 1-20mm(T1) ER?
22	N+/N?, 21 - 50 mm (T2), ER unknown	N+/N? 21-50mm(T2)ER?
23	N+/N?, 51 - 100 mm (T3), ER unknown	N+/N?51-100mm(T3)ER?
24	N+/N?, > 100 mm (T3+/T4), ER unknown	N+N?>100mm(T3+T4)ER?
25	N+/N?, other / unknown size, ER unknown	N+/N? othr/size? ER?
26	N+/N?, 1 - 20 mm (T1), ER+	N+/N? 1-20mm(T1) ER+
27	N+/N?, 21 - 50 mm (T2), ER+	N+/N? 21-50mm(T2)ER+
28	N+/N?, 51 - 100 mm (T3), ER+	N+/N?51-100mm(T3)ER+
29	N+/N?, > 100 mm (T3+/T4), ER+	N+N?>100mm(T3+T4)ER+
30	N+/N?, other / unknown size, ER+	N+/N? othr/size? ER+

Entry Age and Nodal Status

AN4

	Stratum	Abbreviation
1	Entry age less than 50, N0/N-	Age < 50, N0/N-
2	Entry age less than 50, N unknown	Age < 50, N?
3	Entry age less than 50, N+	Age < 50, N+
4	Entry age 50 - 69, N0/N-	Age 50 - 69, N0/N-
5	Entry age 50 - 69, N unknown	Age 50 - 69, N?
6	Entry age 50 - 69, N+	Age 50 - 69, N+
7	Entry age 70 or more, N0/N-	Age 70+, N0/N-
8	Entry age 70 or more, N unknown	Age 70+, N?
9	Entry age 70 or more, N+	Age 70+, N+
10	Entry age unknown, N0/N-	Age ?, N0/N-
11	Entry age unknown, N unknown	Age ?, N?
12	Entry age unknown, N+	Age ?, N+

Regrouping 86 of Entry Age and Nodal Status

-2

	Stratum	Abbreviation
1	Entry age less than 50	Age < 50
2	Entry age 50 - 69	Age 50 - 69
3	Entry age 70 or more	Age 70+
4	Entry age unknown	Age ?

Grade, Age and Nodal Status

ANG2

	Stratum	Abbreviation
1	Well-differentiated, entry age less than 50, N0/N-	Well, < 50, N0/N-
2	Moderately-diff., entry age less than 50, N0/N-	Moderate, <50, N0/N-
3	Poorly-differentiated, entry less than 50, N0/N-	Poor, < 50, N0/N-
4	Primary grade unknown, entry less than 50, N0/N-	Grade ?, < 50, N0/N-
5	Well-differentiated, entry age less than 50, N?	Well, < 50, N?
6	Moderately-diff., entry age less than 50, N?	Moderate, <50, N?
7	Poorly-differentiated, entry less than 50, N?	Poor, < 50, N?
8	Primary grade unknown, entry less than 50, N?	Grade ?, < 50, N?
9	Well-differentiated, entry age less than 50, N+	Well, < 50, N+
10	Moderately-diff., entry age less than 50, N+	Moderate, <50, N+
11	Poorly-differentiated, entry less than 50, N+	Poor, < 50, N+
12	Primary grade unknown, entry less than 50, N+	Grade ?, < 50, N+
13	Well-differentiated, entry age 50 - 69, N0/N-	Well, 50-69, N0/N-
14	Moderately-diff., entry age 50 - 69, N0/N-	Moderate,50-69,N0/N-
15	Poorly-differentiated, entry age 50 - 69, N0/N-	Poor, 50-69, N0/N-
16	Primary grade unknown, entry age 50 - 69, N0/N-	Grade ?,50-69, N0/N-
17	Well-differentiated, entry age 50 - 69, N?	Well, 50-69, N?
18	Moderately-diff., entry age 50 - 69, N?	Moderate, 50-69, N?
19	Poorly-differentiated, entry age 50 - 69, N?	Poor, 50-69, N?
20	Primary grade unknown, entry age 50 - 69, N?	Grade ?, 50-69, N?
21	Well-differentiated, entry age 50 - 69, N+	Well, 50-69, N+
22	Moderately-diff., entry age 50 - 69, N+	Moderate, 50-69, N+
23	Poorly-differentiated, entry age 50 - 69, N+	Poor, 50-69, N+
24	Primary grade unknown, entry age 50 - 69, N+	Grade ?, 50-69, N+
25	Well-differentiated, entry age 70 or more, N0/N-	Well, 70+, N0/N-
26	Moderately-diff., entry age 70 or more, N0/N-	Moderate, 70+, N0/N-
27	Poorly-differentiated, entry age 70 or more, N0/N-	Poor, 70+, N0/N-
28	Primary grade unknown, entry age 70 or more, N0/N-	Grade ?, 70+, N0/N-
29	Well-differentiated, entry age 70 or more, N?	Well, 70+, N?
30	Moderately-diff., entry age 70 or more, N?	Moderate, 70+, N?
31	Poorly-differentiated, entry age 70 or more, N?	Poor, 70+, N?
32	Primary grade unknown, entry age 70 or more, N?	Grade ?, 70+, N?
33	Well-differentiated, entry age 70 or more, N+	Well, 70+, N+
34	Moderately-diff., entry age 70 or more, N+	Moderate, 70+, N+
35	Poorly-differentiated, entry age 70 or more, N+	Poor, 70+, N+
36	Primary grade unknown, entry age 70 or more, N+	Grade ?, 70+, N+
37	Well-differentiated, entry age unknown, N0/N-	Well, Age ?, N0/N-
38	Moderately-diff., entry age unknown, N0/N-	Moderate,Age ?,N0/N-
39	Poorly-differentiated, entry age unknown, N0/N-	Poor, Age ?, N0/N-
40	Primary grade unknown, entry age unknown, N0/N-	Grade ?, Age ?,N0/N-
41	Well-differentiated, entry age unknown, N?	Well, Age ?, N?
42	Moderately-diff., entry age unknown, N?	Moderate, Age ?, N?
43	Poorly-differentiated, entry age unknown, N?	Poor, Age ?, N?
44	Primary grade unknown, entry age unknown, N?	Grade ?, Age ?, N?
45	Well-differentiated, entry age unknown, N+	Well, Age ?, N+
46	Moderately-diff., entry age unknown, N+	Moderate, Age ?, N+
47	Poorly-differentiated, entry age unknown, N+	Poor, Age ?, N+
48	Primary grade unknown, entry age unknown, N+	Grade ?, Age ?, N+

Regrouping 84 of Grade, Age and Nodal Status

-2

	Stratum	Abbreviation
1	Well-differentiated, entry age less than 50	Well, Age < 50
2	Moderately-diff., entry age less than 50	Moderate, Age < 50
3	Poorly-differentiated, entry age less than 50	Poor, Age < 50
4	Primary grade unknown, entry age less than 50	Grade ?, Age < 50
5	Well-differentiated, entry age 50 - 69	Well, Age 50-69
6	Moderately-diff., entry age 50 - 69	Moderate, Age 50-69
7	Poorly-differentiated, entry age 50 - 69	Poor, Age 50-69
8	Primary grade unknown, entry age 50 - 69	Grade ?, Age 50-69
9	Well-differentiated, entry age 70 or more	Well, Age 70+
10	Moderately-diff., entry age 70 or more	Moderate, Age 70+
11	Poorly-differentiated, entry age 70 or more	Poor, Age 70+
12	Primary grade unknown, entry age 70 or more	Grade ?, Age 70+
13	Well-differentiated, entry age unknown	Well, Age ?
14	Moderately-diff., entry age unknown	Moderate, Age ?
15	Poorly-differentiated, entry age unknown	Poor, Age ?
16	Primary grade unknown, entry age unknown	Grade ?, Age ?

Tumour Size, Age & Nodal Stat.

ATN3

	Stratum	Abbreviation
1	T1 (1 - 20mm), entry age less than 50, N0/N-	1-20mm, < 50, N0/N-
2	T1 (1 - 20mm), entry age less than 50, N unknown	1-20mm, < 50, N?
3	T1 (1 - 20mm), entry age less than 50, N+	1-20mm, < 50, N+
4	T2 (21 - 50mm), entry age less than 50, N0/N-	21-50mm, < 50, N0/N-
5	T2 (21 - 50mm), entry age less than 50, N unknown	21-50mm, < 50, N?
6	T2 (21 - 50mm), entry age less than 50, N+	21-50mm, < 50, N+
7	T3-T4 (> 50mm), entry age less than 50, N0/N-	> 50mm, < 50, N0/N-
8	T3-T4 (> 50mm), entry age less than 50, N unknown	> 50mm, < 50, N?
9	T3-T4 (> 50mm), entry age less than 50, N+	> 50mm, < 50, N+
10	Other / unknown size, entry age less than 50, N0/N-	Othr/size?,<50,N0/N-
11	Other / unknown size, entry age less than 50, N unknown	Other/size ?,< 50,N?
12	Other / unknown size, entry age less than 50, N+	Other/size ?,< 50,N+
13	T1 (1 - 20mm), entry age 50 - 69, N0/N-	1-20mm, 50-69, N0/N-
14	T1 (1 - 20mm), entry age 50 - 69, N unknown	1-20mm, 50-69, N?
15	T1 (1 - 20mm), entry age 50 - 69, N+	1-20mm, 50-69, N+
16	T2 (21 - 50mm), entry age 50 - 69, N0/N-	21-50mm, 50-69,N0/N-
17	T2 (21 - 50mm), entry age 50 - 69, N unknown	21-50mm, 50-69, N?
18	T2 (21 - 50mm), entry age 50 - 69, N+	21-50mm, 50-69, N+
19	T3-T4 (> 50mm), entry age 50 - 69, N0/N-	> 50mm, 50-69, N0/N-
20	T3-T4 (> 50mm), entry age 50 - 69, N unknown	> 50mm, 50-69, N?
21	T3-T4 (> 50mm), entry age 50 - 69, N+	> 50mm, 50-69, N+
22	Other / unknown size, entry age 50 - 69, N0/N-	Oth/siz?,50-69,N0/N-
23	Other / unknown size, entry age 50 - 69, N unknown	Other/size?,50-69,N?
24	Other / unknown size, entry age 50 - 69, N+	Other/size?,50-69,N+
25	T1 (1 - 20mm), entry age 70 or more, N0/N-	1-20mm, 70+, N0/N-
26	T1 (1 - 20mm), entry age 70 or more, N unknown	1-20mm, 70+, N?
27	T1 (1 - 20mm), entry age 70 or more, N+	1-20mm, 70+, N+
28	T2 (21 - 50mm), entry age 70 or more, N0/N-	21-50mm, 70+, N0/N-
29	T2 (21 - 50mm), entry age 70 or more, N unknown	21-50mm, 70+, N?
30	T2 (21 - 50mm), entry age 70 or more, N+	21-50mm, 70+, N+
31	T3-T4 (> 50mm), entry age 70 or more, N0/N-	> 50mm, 70+, N0/N-
32	T3-T4 (> 50mm), entry age 70 or more, N unknown	> 50mm, 70+, N?
33	T3-T4 (> 50mm), entry age 70 or more, N+	> 50mm, 70+, N+
34	Other / unknown size, entry age 70 or more, N0/N-	Othr/size?,70+,,N0/N-
35	Other / unknown size, entry age 70 or more, N unknown	Other/size ?,70+,N?
36	Other / unknown size, entry age 70 or more, N+	Other/size ?,70+,N+
37	T1 (1 - 20mm), entry age unknown, N0/N-	1-20mm, Age ?, N0/N-
38	T1 (1 - 20mm), entry age unknown, N unknown	1-20mm, Age ?, N?
39	T1 (1 - 20mm), entry age unknown, N+	1-20mm, Age ?, N+
40	T2 (21 - 50mm), entry age unknown, N0/N-	21-50mm, Age ?,N0/N-
41	T2 (21 - 50mm), entry age unknown, N unknown	21-50mm, Age ?, N?
42	T2 (21 - 50mm), entry age unknown, N+	21-50mm, Age ?, N+
43	T3-T4 (> 50mm), entry age unknown, N0/N-	> 50mm, Age ?, N0/N-
44	T3-T4 (> 50mm), entry age unknown, N unknown	> 50mm, Age ?, N?
45	T3-T4 (> 50mm), entry age unknown, N+	> 50mm, Age ?, N+
46	Other / unknown size, entry age unknown, N0/N-	Othr/siz?,Age?,N0/N-
47	Other / unknown size, entry age unknown, N unknown	Other/size?,Age ?,N?
48	Other / unknown size, entry age unknown, N+	Other/size?,Age ?,N+

Regrouping 85 of Tumour Size, Age & Nodal Stat

-2

	Stratum	Abbreviation
1	T1 (1 - 20mm), entry age less than 50	1-20mm, Age < 50
2	T2 (21 - 50mm), entry age less than 50	21-50mm, Age < 50
3	T3-T4 (> 50mm), entry age less than 50	> 50mm, Age < 50
4	Other / unknown size, entry age less than 50	Other / size ?, < 50
5	T1 (1 - 20mm), entry age 50 - 69	1-20mm, Age 50-69
6	T2 (21 - 50mm), entry age 50 - 69	21-50mm, Age 50-69
7	T3-T4 (> 50mm), entry age 50 - 69	> 50mm, Age 50-69
8	Other / unknown size, entry age 50 - 69	Other / size?, 50-69
9	T1 (1 - 20mm), entry age 70 or more	1-20mm, Age 70+
10	T2 (21 - 50mm), entry age 70 or more	21-50mm, Age 70+
11	T3-T4 (> 50mm), entry age 70 or more	> 50mm, Age 70+
12	Other / unknown size, entry age 70 or more	Other / size ?, 70+
13	T1 (1 - 20mm), entry age unknown	1-20mm, Age ?
14	T2 (21 - 50mm), entry age unknown	21-50mm, Age ?
15	T3-T4 (> 50mm), entry age unknown	> 50mm, Age ?
16	Other / unknown size, entry age unknown	Other / size ?, Age ?

Grade, Age, Nodal & E.R. Stat.

ANGE

	Stratum	Abbreviation
1	Well-diff., entry age less than 50, N0/N-, ER-poor	Well, < 50,N0/N-,ERp
2	Moderately-diff., age less than 50, N0/N-, ER-poor	Mod., < 50,N0/N-,ERp
3	Poorly-diff., entry less than 50, N0/N-, ER-poor	Poor, < 50,N0/N-,ERp
4	Primary grade ?, age less than 50, N0/N-, ER-poor	Grde?, < 50,N0/N-,ERp
5	Well-diff., entry age less than 50, N+/N?, ER-poor	Well, < 50,N+/?, ERp
6	Moderately-diff., age less than 50, N+/N?, ER-poor	Mod., < 50,N+/?, ERp
7	Poorly-diff., entry less than 50, N+/N?, ER-poor	Poor, < 50,N+/?, ERp
8	Primary grade ?, entry less than 50, N+/N?, ER-poor	Grde?,< 50,N+/?, ERp
9	Well-diff., entry age 50 or more, N0/N-, ER-poor	Well, 50+,N0/N-, ERp
10	Moderately-diff., entry 50 or more, N0/N-, ER-poor	Mod., 50+,N0/N-, ERp
11	Poorly-diff., entry age 50 or more, N0/N-, ER-poor	Poor, 50+,N0/N-, ERp
12	Primary grade ?, entry 50 or more, N0/N-, ER-poor	Grde?,50+,N0/N-, ERp
13	Well-diff., entry age 50 or more, N+/N?, ER-poor	Well, 50+, N+/?, ERp
14	Moderately-diff., entry 50 or more, N+/N?, ER-poor	Mod., 50+, N+/?, ERp
15	Poorly-diff., entry age 50 or more, N+/N?, ER-poor	Poor, 50+, N+/?, ERp
16	Primary grade ?, entry 50 or more, N+/N?, ER-poor	Grde?,50+, N+/?, ERp
17	Well-diff., entry age less than 50, N0/N-, ER+/?	Well,< 50,N0/N-,ER+/?
18	Moderately-diff., entry less than 50, N0/N-, ER+/?	Mod.,< 50,N0/N-,ER+/?
19	Poorly-diff., entry age less than 50, N0/N-, ER+/?	Poor,< 50,N0/N-,ER+/?
20	Primary grade ?, entry less than 50, N0/N-, ER+/?	Grde?,< 50,N0/N-,ER+/?
21	Well-diff., entry age less than 50, N+/N?, ER+/?	Well,< 50,N+/?, ER+/?
22	Moderately-diff., entry less than 50, N+/N?, ER+/?	Mod.,< 50,N+/?, ER+/?
23	Poorly-diff., entry less than 50, N+/N?, ER+/?	Poor,< 50,N+/?, ER+/?
24	Primary grade ?, entry less than 50, N+/N?, ER+/?	Grde?,< 50,N+/?, ER+/?
25	Well-diff., entry age 50 or more, N0/N-, ER+/?	Well,50+,N0/N-,ER+/?
26	Moderately-diff., entry 50 or more, N0/N-, ER+/?	Mod.,50+,N0/N-,ER+/?
27	Poorly-diff., entry age 50 or more, N0/N-, ER+/?	Poor,50+,N0/N-,ER+/?
28	Primary grade ?, entry 50 or more, N0/N-, ER+/?	Grde?,50+,N0/N-,ER+/?
29	Well-diff., entry age 50 or more, N+/N?, ER+/?	Well,50+,N+/?, ER+/?
30	Moderately-diff., entry 50 or more, N+/N?, ER+/?	Mod.,50+,N+/?, ER+/?
31	Poorly-diff., entry age 50 or more, N+/N?, ER+/?	Poor,50+,N+/?, ER+/?
32	Primary grade ?, entry age 50 or more, N+/N?, ER+/?	Grde?,50+,N+/?, ER+/?

Regrouping 88 of Grade, Age, Nodal & E.R. Stat.

-4

	Stratum	Abbreviation
1	Well-differentiated, ER-poor	Well-diff., ER-poor
2	Moderately-differentiated, ER-poor	Moderate, ER-poor
3	Poorly-differentiated, ER-poor	Poor, ER-poor
4	Primary grade unknown, ER-poor	Grade ?, ER-poor
5	Well-differentiated, ER+/unknown	Well-diff., ER+/?
6	Moderately-differentiated, ER+/unknown	Moderate, ER+/?
7	Poorly-differentiated, ER+/unknown	Poor, ER+/?
8	Primary grade unknown, ER+/unknown	Grade ?, ER+/?

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[End of document, updated to 13 May 2005]